Patents Assigned to DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
  • Publication number: 20140193493
    Abstract: The present invention relates to solid dosage forms of oleyl phosphocholine (C18:1-PC), or OlPC, for oral administration. Further, the present invention relates to methods for the preparation of the present solid dosage forms and the use thereof as a medicament and especially a medicament for treatment of parasitic diseases, such as leishmaniasis, chagas and malaria, and cancer both in humans and animals. Specifically, the present invention relates to a solid dosage form comprising: 6 to 25 weight % of the solid dosage form oleyl phosphocholine; 20 to 35 weight % of the solid dosage form lactose; 35 to 50 weight % of the solid dosage form cellulose; 5 to 20 weight % of the solid dosage form croscarmellose; 1 to 10 weight % of the solid dosage form hydroxypropylmethyl cellulose; and 0.05 to 1 weight % of the solid dosage form of a lubricant.
    Type: Application
    Filed: November 21, 2011
    Publication date: July 10, 2014
    Applicant: DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
    Inventor: Bruno Jansen
  • Publication number: 20130345177
    Abstract: The present invention relates to the use of oleyl phosphocholine (C18:1-PC), or OlPC,for the treatment of mycosis, and especially for the treatment of mycosis such as mycosis caused by pathogens belonging to a genus selected from the group consisting of Candida, Aspergillus, Fusarium, Cryptococcus, Microsporum, Sporothrix, Trichophyton and Scedosporium, for example, Candida albicans, Candida parapsilosis, Candida glabrata, Candida krusei, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Fusarium solani, Scedosporium prolifacans, Cryptococcus neoformans, Microsporum canis, Sporothrix schenkii, Trichophyton rubrum, Trichophyton mentagrophytes, Aspergillus fumigatus, Fusarium oxysporum.
    Type: Application
    Filed: February 24, 2012
    Publication date: December 26, 2013
    Applicant: DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
    Inventor: Bruno Jansen
  • Publication number: 20130296277
    Abstract: The present invention relates to pharmaceutical compositions for the treatment of parasitic diseases, cancer, or skin diseases by topical administration and especially ointments for the treatment of leishmaniasis. The present invention further relates to the use of the present ointments for the treatment of parasitic diseases, cancer, or skin diseases and especially ointments for the treatment of leishmaniasis in both humans and animals. Specifically, the present invention relates to pharmaceutical compositions such as ointments and crèmes for the treatment of parasitic diseases, cancer, or skin diseases by topical administration comprising 0.1 to 20 weight %, preferably 0.1 to 10 weight %, more preferably 0.1 to 7 weight %, most preferably 0.5 to 5 weight %, of the pharmaceutical composition oleyl phosphocholine as an active ingredient.
    Type: Application
    Filed: January 12, 2012
    Publication date: November 7, 2013
    Applicant: DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
    Inventors: Frans Herwig Jansen, Annie Marie Fortin