Abstract: An automated monitoring and alignment system to position the mechanical and optical components of a flow cytometer to enhance the consistency, performance, and efficiency of particle sorting and analysis applications.

Abstract: A environmental containment system (16) for a flow cytometer (21) which provides a adjustably controllable environment in which biological particles can be differentiated and droplets separated into collection containers (15).

Abstract: The present invention relates to monoclonal antibodies against the human Mcm3 protein, hybridoma cell lines that produce such antibodies, procedures for the production and their use, pharmaceutical compositions comprising a monoclonal antibody according to the present invention, their use for the prevention and treating of certain diseases as well as methods relating to the prevention and treatment of diseases associated with Mcm3 expression. Monoclonal antibodies according to the invention detect and bind human Mcm3 monospecifically both in immunohistological and immunobiochemical detection systems. The process for the production of these monoclonal antibodies comprises an initial screening of excess hybridoma supernatant with immunobiochemical methods followed by a second screening of positive hybridoma by means of an immunohistochemical method.

Abstract: The present invention relates to monoclonal antibodies against the human Mcm3 protein, hybridoma cell lines, that produce such antibodies, procedures for the production and their use, pharmaceutical compositions comprising a monoclonal antibody according to the present invention, their use for the prevention and treating of certain diseases and well as methods relating to the prevention and treatment of diseases associated with Mcm3 expression. Monoclonal antibodies according to the invention detect and bind human Mcm3 monospecifically both in immunohistological and immunobiochemical detection systems. The process for the production of these monoclonal antibodies comprises an initial screening of excess hybridoma supernatant with immunobiochemical methods followed by a second screening of positive hybridoma by means of an immunohistochemical method.

Abstract: A environmental containment system (16) for a flow cytometer (21) which provides a adjustably controllable environment in which biological particles can be differentiated and droplets separated into collection containers (15).

Abstract: A flow cytometer (20) capable of utilizing an imaging system including a sensor (88) to determine various properties of the flow cytometer (20). Importantly, the imaging allows for determination of a drop delay time (154). Other characteristics that can be determined include at least the width of the stream, pressure of the stream, effect of charged droplets on other droplets (44), trajectory of the stream, resonant frequency, wavelengths, change in position of droplet break-off point (150), and others. An automatic warning system (180) can be used to alert an operator of an anomaly during setup or during normal operation. Furthermore, a mechanical interrupter can be used to shield a sort result from contamination by an incorrectly functioning stream. The cytometer (20) also allows for the disablement of the sort, particularly the charging and deflection systems. In addition, a more accurate system for detecting the speed of the stream can be used.