Abstract: The present invention relates to compositions and methods for identifying, assessing, preventing, and treating melanoma, A variety of PD-L1 isoform biomarkers are provided, wherein alterations in the copy number of one or more of the biomarkers and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers is associated with melanoma status.
Type:
Application
Filed:
January 14, 2015
Publication date:
November 24, 2016
Applicant:
Dana-Farber Camcer Institute, Inc.
Inventors:
F. Stephen Hodi, Jun Zhou, Gordon J. Freeman, Jingjing Li, Xinqi Wu