Patents Assigned to Daniel A. Vallera
  • Publication number: 20120121614
    Abstract: Methods and composition involving genetically engineered targeting conjugates with reversed orientation of VL and VH chains are provided. For example, in certain aspects targeting conjugates comprising VL and VH chains of anti-CD22 and anti-CD19 are described. In a further aspect, the invention provides methods and targeting conjugates comprising therapeutic agents or diagnostic agents for delivery to B cells.
    Type: Application
    Filed: March 11, 2010
    Publication date: May 17, 2012
    Applicants: Jeff Lion, Daniel A. Vallera
    Inventors: Daniel A. Vallera, Jeff Lion