Abstract: The present invention relates to methods for treating nicotine addiction. The method involves administering to the patient an effective amount of a compound having the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen and C1 to C6 alkyl;R.sup.2 is selected from the group consisting of hydrogen, methyl, and ethyl;R.sup.3 is selected from the group consisting of hydrogen, methyl, C1 to C6 alkanoyl, C3 to C6 cycloalkanoyl, and pyridinecarbonyl;Q is a bivalent alkylene moiety; andY is selected from the group consisting of a halo-(C2 to C6)-alkenyl moiety having 1 or 2 chlorine or bromine atoms attached to the ethylenic carbon, a cycloalkyl moiety, a cyano moiety, and a cyano-(C3 to C6)-alkenyl moietyor a pharmaceutically acceptable acid-addition salt thereof.
Type:
Grant
Filed:
July 15, 1997
Date of Patent:
October 12, 1999
Assignees:
Albany Medical College, David Archer, Daniel Archer, Eve Archer