Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same.
Abstract: The present invention relates to a process for producing downstream products, such as fermentable sugars (e.g., glucose) and alcohols (e.g., ethanol) from starch-containing material (e.g., grain) without a pH adjustment before or after the starch liquefaction step.
Type:
Application
Filed:
February 5, 2009
Publication date:
August 27, 2009
Applicant:
DANISCO US INC., GENENCOR DIVISION
Inventors:
Suzanne Breneman, Brad A. Paulson, Vivek Sharma, Jayarama K. Shetty
Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and that exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions generally comprise at least one of an additional enzyme, a detergent, a surfactant, a chelator, an oxidizing agent, an acidulant, an alkalizing agent, a source of peroxide, a source of hardness, a salt, a detergent complexing agent, a polymer, a stabilizing agent, or a fabric conditioner. Also disclosed are detergent formulations comprising the variants. Methods of using the compositions for desizing woven material and washing or cleaning items, such as dishes or laundry, are disclosed. Kits related thereto are also provided.
Abstract: The present invention provides methods and compositions for the efficient and enhanced secretion of a protein of interest from a host cell. In specific, proteins are secreted through the Sec-dependent pathway, involving the spoIIIJ and/or yqjG gene product(s). In some embodiments, expression of the spoIIIJ and/or yqjG gene product(s) is modulated by a promoter operably linked to the gene.
Type:
Grant
Filed:
December 12, 2002
Date of Patent:
June 30, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Sierd Bron, Harold Tjalsma, Jan M. Van Dijl
Abstract: Disclosed are compositions comprising variants of a parent G. stearothermophilus alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
Type:
Grant
Filed:
November 3, 2008
Date of Patent:
June 2, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Scott D. Power, Sandra W. Ramer, Andrew Shaw
Abstract: The present invention provides an endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
Type:
Grant
Filed:
January 10, 2006
Date of Patent:
May 5, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
Abstract: The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same.
Type:
Grant
Filed:
May 12, 2004
Date of Patent:
March 31, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Brian E Jones, William D. Grant, Shaun Heaphy, Susan Grant, Helen C. Rees
Abstract: The present invention relates to novel variant EGIII or EGIII-like cellulases that have improved stability. The variant cellulases have performance sensitive residues replaced to a residue having modified stability.
Type:
Grant
Filed:
May 19, 2003
Date of Patent:
March 10, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Peter Gualfetti, Colin Mitchinson, Jay Phillips
Abstract: The invention relates to at least one nucleotide sequence, derived from a nucleotide sequence encoding an acyltransferase polypeptide comprising at least one membrane-spanning region, encoding an improved active membrane independent acyltransferase polypeptide in which at least one amino acid residue of the membrane-spanning region has been deleted and/or substituted as compared to the original acyltransferase polypeptide, wherein the encoded active membrane independent acyltransferase polypeptide can produce fatty acid esters and/or fatty acid thioesters such as triacylglycerols, diacylglycerols, monoacylglycerols, phospholipids, glycolipids, waxesters, acylated carbohydrates, acylated amino acids, and lysolipids, e.g. lysophosphospholipid, lysolecithin. Thereby one single acyltransferase can be used for the production of a huge number of products.
Type:
Grant
Filed:
May 28, 2003
Date of Patent:
March 3, 2009
Assignee:
Danisco US Inc., Genencor Division
Inventors:
Anders Dahlqvist, Alokesh Ghosal, Ylva Lindqvist, Antoni Banas
Abstract: The present invention provides means to assess immune response profiles of populations. In particular, the present invention provides means to qualitatively assess the immune response of human populations, wherein the immune response directed against any protein of interest is analyzed. The present invention further provides means to rank proteins based on their relative immunogenicity. In further embodiments, the present invention provides means for verifying immunological response data, as well as means for predicting immune responses directed against any antigen/immunogen. In addition, the present invention provides means to create proteins with reduced immunogenicity for use in various applications.