Abstract: Genetic markets for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A3 gene, are located on bovine chromosome BTA3. The G/T polymorphism at position 559 of the bovine SLC35A3 gene is identified as being causative and diagnostic for CVM in cattle.
Type:
Grant
Filed:
November 15, 2001
Date of Patent:
August 22, 2006
Assignees:
Danmarks Jordbrugsforskning, Kvaegavlsforeningen Dansire
Inventors:
Christian Bendixen, Søren Svendsen, Helle Jensen, Frank Panitz, Anders Aasberg, Lars-Erik Holm, Per Horn, Anette Høj, Bo Thomsen, Mette Jeppesen, Hunnicke Vivi Nielsen, Marck Jonker