Abstract: An endoscopic surgical instrument includes at least one endoscopy shaft, with at least one suction and/or rinse unit, with at least one securing element, which is configured to secure the at least one endoscopy shaft on the at least one suction and/or rinse unit in a coupled state, and with at least one fixation unit, which is configured for a captive fixation of the at least one securing element on the at least one suction and/or rinse unit, wherein the at least one fixation unit comprises at least one cover element which, in a mounted state, encompasses the at least one securing element at least partly, wherein the at least one cover element comprises at least one operational recess for an operation of the at least one securing element.