Patents Assigned to DAPING HOSPITAL, ARMY MEDICAL UNIVERSITY
  • Treatment for Inflammatory Bowel Disease and Radiation-induced Intestinal Injury
    Publication number: 20220273763
    Abstract: Compositions for and methods of treating irritable bowel disease are provided. The compositions and methods employ MG53, which can be in the form of recombinant human MG53. The MG53 can be administered in a form to avoid or bypass gastric digestion or degradation. The composition can include a live MG53-expressing microbe, such as a probiotic composition that expresses MG53 in the gastrointestinal tract of a subject. An enteric release composition comprising MG53 is also provided.
    Type: Application
    Filed: May 10, 2022
    Publication date: September 1, 2022
    Applicants: OHIO STATE INNOVATION FOUNDATION, DAPING HOSPITAL, ARMY MEDICAL UNIVERSITY, Institute of Microbiology, Chinese Academy of Sciences
    Inventors: Jianjie MA, Chunyu ZENG, Yu HAN, Donghai YANG, Zhengfang GONG, Zhongshu ZHOU, Jin ZHONG
  • Composition for and Method of Treating Hepatic Tissue Injury
    Publication number: 20220105152
    Abstract: Compositions for and methods of treating liver injury are provided. Said compositions comprise MG53 or express MG53. Said compositions can be used for treating chronic or acute injured liver tissue and can be administered systemically, locally, or both.
    Type: Application
    Filed: December 13, 2021
    Publication date: April 7, 2022
    Applicants: OHIO STATE INNOVATION FOUNDATION, DAPING HOSPITAL, ARMY MEDICAL UNIVERSITY
    Inventors: CHUNYU ZENG, Yu HAN, Jianjie MA, Tao TAN