Patents Assigned to Darwin Discover Limited
  • Benzofuran carboxamides and their therapeutic use
    Patent number: 5972936
    Abstract: Compounds having the formula (i), ##STR1## wherein the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined herein. The compounds of the present invention can be utilized to treat disease states capable of being modulated by inhibition of proteins which mediate cellular activity, such as tumor necrosis factor (TNF) and/or phosphodiesterase IV (PDE IV).
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: October 26, 1999
    Assignee: Darwin Discover Limited
    Inventors: Hazel Joan Dyke, John Gary Montana