Patents Assigned to DATWYLER PHARMA PACKAGING INTERNATIONAL NV
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Patent number: 11395883Abstract: A plunger for a medical syringe includes a plunger body having a longitudinal axis, a lateral surface, a front side and a rear side, wherein a first sealing bead is associated with the front side of the plunger, the rear side is used for connecting to a plunger rod and, in addition, a front part of the plunger including the front side is covered with a film-like cover layer for otherwise separating the plunger from the medical substance in the use position. In addition, the cover layer be configured with different thicknesses, wherein the thickness is greatest in the region of the longitudinal axis and decreases radially outwards from the longitudinal axis.Type: GrantFiled: December 4, 2017Date of Patent: July 26, 2022Assignees: Datwyler Pharma Packaging International NV, Hasselt UniversiteitInventors: Anita Thijs, Bram Jongen, Wim Deferme, Inge Verboven
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Patent number: 10836892Abstract: The material of a part includes a composition obtained by blending an isobutylene-based, pre-crosslinked polymer as component (A), at least one poly olefin or a non-crosslinked rubber or a TPV as component (B), at least one polymer having a Tg of 90° C. or higher as component (C) and—preferably—at least one component (D) selected from the group of: substituted vinyl polymers, stryrenic block copolymers, inorganic functionalized and non-functionalized fillers, carbon black, halogen scavengers, preferably the inorganic halogen scavengers, acid acceptors, stabilizers, preferably the polymeric stabilizers, and processing aids.Type: GrantFiled: July 12, 2013Date of Patent: November 17, 2020Assignee: Datwyler Pharma Packaging International NVInventors: Leszek Jakuczek, Luc Vanderheyden, Agna Francis
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Publication number: 20190307964Abstract: A plunger for a medical syringe includes a plunger body having a longitudinal axis, a lateral surface, a front side and a rear side, wherein a first sealing bead is associated with the front side of the plunger, the rear side is used for connecting to a plunger rod and, in addition, a front part of the plunger including the front side is covered with a film-like cover layer for otherwise separating the plunger from the medical substance in the use position. In addition, the cover layer be configured with different thicknesses, wherein the thickness is greatest in the region of the longitudinal axis and decreases radially outwards from the longitudinal axis.Type: ApplicationFiled: December 4, 2017Publication date: October 10, 2019Applicants: Datwyler Pharma Packaging International NV, Hasselt UniversiteitInventors: Anita THIJS, Bram JONGEN, Wim DEFERME, Inge VERBOVEN
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Patent number: 10273059Abstract: A closure stopper for pharmaceutical applications has a sealing flange seating in a sealing manner on an end face of the container's closure mouth. The sealing flange has a lower sealing surface and a boundary plane contacting an area protruding farthest downwardly and extending perpendicularly to the closure stopper's center axis. An engagement portion extending below the sealing flange is formed with a smaller radial extent than the sealing flange. Preferably a handling portion extends above the sealing flange. A circumferential sealing projection also is formed on the engagement portion and protrudes by a radial dimension with respect to an axial portion of the engagement portion initially adjoining the sealing flange from underneath and having a portion-radius. The sealing projection, at least with respect to its base portion, vertically overlaps a set-back region formed on the sealing flange and set back with respect to the contact plane.Type: GrantFiled: September 1, 2011Date of Patent: April 30, 2019Assignee: Datwyler Pharma Packaging International NVInventors: Ronny Prosper Elisabeth Vrijens, Reinhard Louis Jozef Waeben
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Patent number: 9540154Abstract: A closure (1) for a container (9), or for an ampoule (9), in which a medicament is accommodated, having a closure cap (2) and a closure stopper (5) accommodated in the closure (2). Detent moldings (6) are formed on the closure cap (2) for latchingly holding the closure (1) on the ampoule (9), and a sliding part (3) is provided which is movable relative to the closure cap (2) in order to displace the closure stopper (5) into the closed position. In order to advantageously provide, with respect to carrying out a freeze-drying process, a closure for a container, or for an ampoule, in which a medicament is accommodated, the closure stopper (5) is displaceable relative to the cap (2) by means of the sliding part (3) in order to move the closure stopper into the closed position. There is also a method for carrying out a freeze-drying process for a medium, or for a medicament, which is accommodated in a container, or in an ampoule (9).Type: GrantFiled: May 6, 2011Date of Patent: January 10, 2017Assignee: Datwyler Pharma Packaging International NVInventors: Ronny Prosper Elisabeth Vrijens, Reinhard Louis Jozef Waeben
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Publication number: 20160137825Abstract: The material of a part includes a composition obtained by blending an isobutylene-based, pre-crosslinked polymer as component (A), at least one poly olefin or a non-crosslinked rubber or a TPV as component (B), at least one polymer having a Tg of 90° C. or higher as component (C) and—preferably—at least one component (D) selected from the group of: substituted vinyl polymers, stryrenic block copolymers, inorganic functionalized and non-functionalized fillers, carbon black, halogen scavengers, preferably the inorganic halogen scavengers, acid acceptors, stabilizers, preferably the polymeric stabilizers, and processing aids.Type: ApplicationFiled: July 12, 2013Publication date: May 19, 2016Applicant: Datwyler Pharma Packaging International NVInventors: Leszek JAKUCZEK, Luc VANDERHEYDEN, Agna FRANCIS
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Publication number: 20150298414Abstract: A method produces a flanged cap and a flanged cap for a vessel accommodates a pharmaceutical substance, particularly a vial, wherein the flanged cap is formed from one material strip (M) having a film layer that has already been plastic-coated, wherein the material strip is thereafter stamped out and shaped via deep-drawing. A plastic component is affixed on the plastic coating of the flanged cap that forms a plastic layer. A flanged cap for a vessel for accommodating a pharmaceutical substance, particularly a vial, is formed from a metal film layer, wherein the film layer is likewise covered on the outside with a plastic layer that forms a coating on the film layer. A vessel contains a pharmaceutical substance.Type: ApplicationFiled: March 21, 2013Publication date: October 22, 2015Applicant: Datwyler Pharma Packaging International NVInventors: Ralf DITTMER, Ronny Prosper Elisabeth VRIJENS
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Publication number: 20130213924Abstract: A closure stopper for pharmaceutical applications has a sealing flange seating in a sealing manner on an end face of the container's closure mouth. The sealing flange has a lower sealing surface and a boundary plane contacting an area protruding farthest downwardly and extending perpendicularly to the closure stopper's center axis. An engagement portion extending below the sealing flange is formed with a smaller radial extent than the sealing flange. Preferably a handling portion extends above the sealing flange. A circumferential sealing projection also is formed on the engagement portion and protrudes by a radial dimension with respect to an axial portion of the engagement portion initially adjoining the sealing flange from underneath and having a portion-radius. The sealing projection, at least with respect to its base portion, vertically overlaps a set-back region formed on the sealing flange and set back with respect to the contact plane.Type: ApplicationFiled: September 1, 2011Publication date: August 22, 2013Applicant: Datwyler Pharma Packaging International NVInventors: Ronny Prosper Elisabeth Vrijens, Reinhard Louis Jozef Waeben
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Publication number: 20130055681Abstract: The invention relates in first instance to a closure (1) for a container (9), for example an ampoule (9), in which preferably a medicament is accommodated, having a closure cap (2) and a closure stopper (5) accommodated in the closure (2). Detent moldings (6) are formed on the closure cap (2) for latchingly holding the closure (1) on the ampoule (9), and a sliding part (3) is provided which is movable relative to the closure cap (2) in order to displace the closure stopper (5) into the closed position, In order to advantageously provide, with respect to carrying out a freeze-drying process, a closure for a container, in particular an ampoule, in which a medicament is accommodated, it is proposed that the closure stopper (5) is displaceable relative to the cap (2) by means of the sliding part (3) in order to move the closure stopper into the closed position.Type: ApplicationFiled: May 6, 2011Publication date: March 7, 2013Applicant: DATWYLER PHARMA PACKAGING INTERNATIONAL NVInventors: Ronny Prosper Elisabeth Vrijens, Reinhard Louis Jozef Waeben