Patents Assigned to Davol, Inc.
  • Patent number: 11413129
    Abstract: An implantable prosthesis for repairing a defect in a muscle or tissue wall. The prosthesis comprises a body of biologically compatible prosthetic material having a preformed three-dimensional contoured shape that independently assumes a three-dimensional curved shape configured to conform to the muscle or tissue wall. The body may be formed of a mesh fabric employing a knit construction. The body may be configured with one or more mechanical characteristics, individually or in any combination, having defined properties which may enhance the ability of the prosthesis to be handled in a surgical, robotic environment while meeting the performance and physical characteristics for soft tissue repair and reconstruction. One or more visual indicia may be provided to facilitate positioning and/or placement of the prosthesis at the muscle or tissue wall.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: August 16, 2022
    Assignee: Davol Inc.
    Inventors: Augustus Felix, Talia D'Ambruoso, Cuixiang Qu Spinney, Korel Cudmore
  • Publication number: 20220211900
    Abstract: Compositions and methods related to powdered hemostats that crosslink during and/or after application to a bleeding site are described. The compositions may comprise a first component comprising a multifunctionalized polymeric composition (e.g., multifunctionalized polyethylene glycol) functionalized with electrophilic reactive groups, and a second component that comprises a protein such as albumin. The compositions may in certain applications act as hemostats when applied in dry powder form to a bleeding wound, whereupon the first component and the second component of the composition crosslink to form a hydrogel.
    Type: Application
    Filed: December 27, 2021
    Publication date: July 7, 2022
    Applicant: Davol Inc.
    Inventors: Keith Greenawalt, Frederick H. Strickler, JR.
  • Publication number: 20220160351
    Abstract: Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. In some embodiments, the surgical instrument may include a magnetic preload lock-out to place the follower in a zero-load state in which the follower does not apply a preload to the fasteners.
    Type: Application
    Filed: April 15, 2020
    Publication date: May 26, 2022
    Applicant: Davol Inc.
    Inventor: Augustus Felix
  • Publication number: 20220047369
    Abstract: Embodiments disclosed herein relate to prosthetics for augmenting or repairing a tissue defect, such as a ventral or incisional hernia. In some embodiments, a repair prosthetic may include a patch body and a first fastener attached to a first portion of the patch body. A coupler may be attached to and extend from a second portion of the patch body, and a second fastener may be attached to the second portion of the patch body via the coupler. The coupler may be retracted relative to the second portion of the patch body or the second fastener to apply tension to the patch body in some embodiments.
    Type: Application
    Filed: October 3, 2019
    Publication date: February 17, 2022
    Applicant: Davol Inc.
    Inventor: Joshua Yao Guo
  • Publication number: 20220002444
    Abstract: Compositions and methods related to powdered hemostats that crosslink during and/or after application to a bleeding site are generally described.
    Type: Application
    Filed: July 1, 2021
    Publication date: January 6, 2022
    Applicant: Davol Inc.
    Inventors: Keith Greenawalt, Christopher Bowley, Jessica Powell, Rajendra R. Bhat, Michael T. Cash, Aaron D. Strickland, Esther M. Valliant, Frederick H. Strickler, JR., Andrew C. Yang
  • Publication number: 20220001075
    Abstract: Compositions and methods related to flowable hemostats that crosslink during and/or after application to a bleeding site are generally described.
    Type: Application
    Filed: July 1, 2021
    Publication date: January 6, 2022
    Applicant: Davol Inc.
    Inventors: Keith Greenawalt, Christopher Bowley, Frederick H. Strickler, JR., Andrew C. Yang, Rajendra R. Bhat, Jessica Powell, Michael T. Cash, Aaron D. Strickland, Esther M. Valliant
  • Publication number: 20210402106
    Abstract: Therapeutic powder applicators and their methods of operation are described. In some embodiments, a first flow of gas may flow through a distal porous portion of a chamber containing a therapeutic powder. This gas may fluidize and entrain the therapeutic powder and flow the entrained powder through an outlet that is in fluid communication with the chamber.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 30, 2021
    Applicant: Davol Inc.
    Inventors: Jonathan Bruce Trexler, Oliver Sowerby, Steve McLellan, Michael Herd, Charles Lowndes, Jon Jamin
  • Patent number: 11191604
    Abstract: A surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. The fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. The surgical instrument may include a removable preload lock-out attached to the elongated shaft to prevent the follower from applying a preload to the fasteners.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: December 7, 2021
    Assignee: Davol Inc.
    Inventors: Nathan Stewart Cauldwell, Donald E. Ziniti, Derek Affonce, Justin Lewis, Augustus Felix, Talia D'Ambruoso
  • Publication number: 20210228304
    Abstract: Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. In some embodiments, the surgical instrument may include a removable preload lock-out attached to the elongated shaft to prevent the follower from applying a preload to the fasteners.
    Type: Application
    Filed: April 13, 2021
    Publication date: July 29, 2021
    Applicant: Davol Inc.
    Inventors: Nathan Stewart Cauldwell, Donald E. Ziniti, Derek Affonce, Justin Lewis, Augustus Felix, Talia D'Ambruoso
  • Publication number: 20210169628
    Abstract: An elongate open-bored applicator (EOBP) adapted to deploy a mesh comprising (a) at least one inflatable contour-balloon, (b) at least one inflatable dissection balloon. The inflatable contour-balloon and the inflatable dissection balloon are adjustable and located at the distal portion; and, (c) at least one actuating means located at the proximal portion. The actuating means is in communication with the inflatable contour-balloon and the inflatable dissection balloon. The actuating means is adapted to provide the inflatable contour-balloon and the inflatable dissection balloon with independent activation and/or de-activation.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 10, 2021
    Applicant: Davol Inc.
    Inventors: Mordehai Sholev, Amir Szold, Ibrahim Matter, Ziv Tamir
  • Patent number: 11013501
    Abstract: Methods for protecting a peritoneum or other tissue during a surgical procedure are disclosed. In some embodiments, a protective lining is applied to the peritoneum or other tissue before an active surgical intervention, such as before tissue dissection, tissue approximation, and/or other surgical act. In some embodiments, the protective lining includes a protective film applied to the peritoneum or other tissue via a delivery balloon or via a spray instrument.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: May 25, 2021
    Assignee: Davol, Inc.
    Inventors: Devang Vijay Shah, Robert Richard, Christopher Bowley
  • Patent number: 11007030
    Abstract: Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. In some embodiments, the surgical instrument may include a removable preload lock-out attached to the elongated shaft to prevent the follower from applying a preload to the fasteners.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: May 18, 2021
    Assignee: Davol Inc.
    Inventors: Nathan Stewart Cauldwell, Donald E. Ziniti, Derek Affonce, Justin Lewis, Augustus Felix, Talia D'Ambruoso
  • Publication number: 20210128289
    Abstract: A hernia repair device, comprising: an inflatable balloon having an inflation tube, the inflation tube having a proximal end attached to said balloon and a distal end adapted to be extracted from the body, separately from the balloon, via an opening which is smaller than a laparoscopic opening; and a mesh removably attached to said balloon, wherein the inflation tube passes through the mesh.
    Type: Application
    Filed: November 11, 2020
    Publication date: May 6, 2021
    Applicant: Davol Inc.
    Inventor: Mordehai Sholev
  • Publication number: 20210045862
    Abstract: The present invention provides a fixating means adapted for use in hernia repair surgeries in attaching a mesh and mesh deployment means; said fixating means are attached to said mesh deployment means; and fixating means comprising: (a) a first portion coupled to said deployment means; and, (b) a second portion comprising a coil having a predetermined retracted shape; said coil is reconfigurable from a plurality of unretracted positions to a plurality of retracted positions and from said plurality of retracted positions to said plurality of unretracted positions; wherein said attachment between said deployment means and said mesh is obtained by reconfiguration of said coil from at least one of said unretracted positions to at least one of said retracted positions.
    Type: Application
    Filed: July 21, 2020
    Publication date: February 18, 2021
    Applicant: Davol Inc.
    Inventors: Mordehai Sholev, Ruth Zajdman, Itay Ben-Nun
  • Patent number: 10898309
    Abstract: An elongate open-bored applicator (EOBP) adapted to deploy a mesh comprising (a) at least one inflatable contour-balloon, (b) at least one inflatable dissection balloon. The inflatable contour-balloon and the inflatable dissection balloon are adjustable and located at the distal portion; and, (c) at least one actuating means located at the proximal portion. The actuating means is in communication with the inflatable contour-balloon and the inflatable dissection balloon. The actuating means is adapted to provide the inflatable contour-balloon and the inflatable dissection balloon with independent activation and/or de-activation.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: January 26, 2021
    Assignee: Davol Inc.
    Inventors: Mordehai Sholev, Amir Szold, Ibrahim Matter, Ziv Tamir
  • Patent number: 10864068
    Abstract: A hernia repair device, comprising: an inflatable balloon having an inflation tube, the inflation tube having a proximal end attached to said balloon and a distal end adapted to be extracted from the body, separately from the balloon, via an opening which is smaller than a laparoscopic opening, and a mesh removably attached to said balloon, wherein the inflation tube passes through the mesh.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 15, 2020
    Assignee: Davol Inc.
    Inventor: Mordehai Sholev
  • Patent number: 10751156
    Abstract: The present invention provides a fixating means adapted for use in hernia repair surgeries in attaching a mesh and mesh deployment means; said fixating means are attached to said mesh deployment means; and fixating means comprising: (a) a first portion coupled to said deployment means; and, (b) a second portion comprising a coil having a predetermined retracted shape; said coil is reconfigurable from a plurality of unretracted positions to a plurality of retracted positions and from said plurality of retracted positions to said plurality of unretracted positions; wherein said attachment between said deployment means and said mesh is obtained by reconfiguration of said coil from at least one of said unretracted positions to at least one of said retracted positions.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: August 25, 2020
    Assignee: Davol Inc.
    Inventors: Mordehai Sholev, Ruth Zajdman, Itay Ben-Nun
  • Publication number: 20200261624
    Abstract: Articles and methods involving soft tissue repair implants comprising 2-hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or their conjugate acids are generally provided. The 2-hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or the conjugate acid(s) of 2-hydroxybutyrate, 3-hydroxybutyrate, and 4-hydroxybutyrate may be provided in a therapeutically-effective amount for reducing or preventing microbial infection.
    Type: Application
    Filed: October 24, 2018
    Publication date: August 20, 2020
    Applicants: Davol Inc., University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: Peter Maughan Crapo, Devang Vijay Shah, Stephen F. Badylak, George Hussey, Catalina Pineda Molina, Brian Sicari
  • Publication number: 20200015809
    Abstract: Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. In some embodiments, the surgical instrument may include a removable preload lock-out attached to the elongated shaft to prevent the follower from applying a preload to the fasteners.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 16, 2020
    Applicant: Davol Inc.
    Inventors: Nathan Stewart Cauldwell, Donald E. Ziniti, Derek Affonce, Justin Lewis, Augustus Felix, Talia D'Ambruoso
  • Publication number: 20200015922
    Abstract: Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft including a reciprocating driveshaft disposed within the elongated shaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft for displacing one or more fasteners within the elongated shaft towards a distal fastener deployment position. In some embodiments, the surgical instrument may include a removable preload lock-out attached to the elongated shaft to prevent the follower from applying a preload to the fasteners.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 16, 2020
    Applicant: Davol Inc.
    Inventors: Nathan Stewart Cauldwell, Derek Affonce, Augustus Felix, Talia D'Ambruoso