Patents Assigned to Daya Drug Discoveries, Inc.
  • Pyridoindolobenz[b,d]azepine derivatives and uses thereof
    Patent number: 9822117
    Abstract: The present invention discloses pyridoindolobenz[b,d]azepines compositions of Formula 1, wherein Y is a single bond or a double bond. A and B are independently —(CH2)n—; and ‘n’ varies from 0 to 3. R1 to R10 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Grant
    Filed: March 2, 2014
    Date of Patent: November 21, 2017
    Assignee: DAYA DRUG DISCOVERIES, INC.
    Inventor: Parthasarathi Rajagopalan
  • Pentacyclic pyridoindolobenzo[b,e]diazepines and thiazepines for treating CNS disorders
    Patent number: 9695199
    Abstract: The present invention discloses pyridoinolobenzo[b,e]diazepine and thiazepine derivatives of Formula 1, wherein X is NR10, S, S(O), or S(O)2. Y is a single bond or no bond. A and B are independently (CH2)m and (CH2)n respectively; and the subscripts ‘m’ and ‘n’ independently vary from 1 to 4. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: July 4, 2017
    Assignee: DAYA DRUG DISCOVERIES, INC.
    Inventor: Parthasarathi Rajagopalan
  • PENTACYCLIC PYRIDOINDOLOBENZO[b,e]DIAZEPINES AND THIAZEPINES FOR TREATING CNS DISORDERS
    Publication number: 20170174708
    Abstract: The present invention discloses pyridoinolobenzo[b,e]diazepine and thiazepine derivatives of Formula 1, wherein X is NR10, S, S(O), or S(O)2. Y is a single bond or no bond. A and B are independently (CH2)m and (CH2)n respectively; and the subscripts ‘m’ and ‘n’ independently vary from 1 to 4. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Application
    Filed: February 6, 2017
    Publication date: June 22, 2017
    Applicant: Daya Drug Discoveries, Inc.
    Inventor: Parthasarathi Rajagopalan
  • Substituted benzo[5,6]azepino[3,2,1-hi]pyrido[4,3-b]indoles and substituted benzo[6,7][1,4]oxazepino[2,3,4-hi]pyrido[4,3-b]indoles for treating CNS disorders
    Patent number: 9598414
    Abstract: The present invention discloses pyridoinolobenz[b,e]azepine derivatives of Formula 1, wherein X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. A and B are independently —(CH2)n—; and ‘n’ varies from 0 to 3. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Grant
    Filed: March 2, 2014
    Date of Patent: March 21, 2017
    Assignee: DAYA DRUG DISCOVERIES, INC.
    Inventor: Parthasarathi Rajagopalan
  • PYRIDOINDOLOBENZ[B,E]AZEPINE DERIVATIVES AND USES THEREOF
    Publication number: 20160039820
    Abstract: The present invention discloses pridoinolobenz[b,c]azepine derivatives of Formula 1, wherein X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. A and B are independently —(CH2)n—; and ‘n’ varies from 0 to 3. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Application
    Filed: March 2, 2014
    Publication date: February 11, 2016
    Applicant: Daya Drug Discoveries, Inc.
    Inventor: Parthasarathi Rajagopalan
  • PYRIDOINDOLOBENZ[B,D]AZEPINE DERIVATIVES AND USES THEREOF
    Publication number: 20160002237
    Abstract: The present invention discloses pyridoindolobenz[b,d]azepines compositions of Formula 1, wherein Y is a single bond or a double bond. A and B are independently —(CH2)n—; and ‘n’ varies from 0 to 3. R1 to R10 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Application
    Filed: March 2, 2014
    Publication date: January 7, 2016
    Applicant: Daya Drug Discoveries, Inc.
    Inventor: Parthasarathi Rajagopalan
  • Pyridoindolobenzox—and thiazepine derivatives and uses thereof
    Patent number: 8367655
    Abstract: The present invention discloses pyridoindolobenzox- and thiazepine compositions of Formula 1, wherein A is —CH(R9)—X—, —XCH(R9)—; —CO—X— or —X—CO—; X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. D and E are independently —(CH2)n—; and ‘n’ varies from 0 to 2. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: February 5, 2013
    Assignee: Daya Drug Discoveries, Inc.
    Inventor: Parthasarathi Rajagopalan
  • Pyridoindolobenzox-and thiazepine derivatives and uses thereof
    Publication number: 20110003840
    Abstract: The present invention discloses pyridoindolobenzox- and thiazepine compositions of Formula 1, wherein A is —CH(R9)—X—, —XCH(R9)—; —CO—X— or —X—CO—; X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. D and E are independently —(CH2)n—; and ‘n’ varies from 0 to 2. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
    Type: Application
    Filed: July 2, 2010
    Publication date: January 6, 2011
    Applicant: Daya Drug Discoveries, Inc.
    Inventor: Parthasarathi Rajagopalan