Abstract: The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.

Abstract: The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.

Abstract: The present invention relates to compositions and methods for preventing allergy in a subject. Particularly, the present invention relates to epicutaneous prevention of allergies in children. The invention also relates to compositions for use in such methods, as well as their manufacture. The invention may be used to cause protection against any allergy, particularly food or respiratory allergies.

Abstract: The invention concerns the development of a system to deliver vaccines via cutaneous route. The invention more particularly concerns the use of a device comprising a condensation compartment for epicutaneous vaccination. The invention also concerns protocols for epicutaneous vaccination allowing an efficient immune response to be obtained without any skin treatment. The invention can be implemented in any mammal, preferably in human beings, to induce a therapeutic or preventive immune response against any type of antigen.

Abstract: The present invention relates to the treatment of EE. More specifically, the invention relates to a new method of treating EE through the epicutaneous route. In particular, the method of the invention comprises applying to the skin of the subject a skin patch device, comprising a composition, under conditions allowing a contact between said composition and the skin. The present invention also relates to the skin patch device and to a use of the skin patch device in the manufacture of a composition for treating eosinophilic esophagitis in a subject.

Abstract: The present invention relates to compositions and methods for preventing allergy in a subject. Particularly, the present invention relates to epicutaneous prevention of allergies in children. The invention also relates to compositions for use in such methods, as well as their manufacture. The invention may be used to cause protection against any allergy, particularly food or respiratory allergies.

Abstract: The present disclosure provides a device (1) for the cutaneous application of a substance (2) that contains: a patch (3) containing the substance (2); and a single-use wrist strap (4) containing an irreversible attachment system for maintaining the substance (2) of the patch (3) against the skin of a subject.

Abstract: The present invention relates to improved methods for vaccination of a subject. Particularly, the present invention discloses the use of skin antigen application to amplify and improve a pre-existing immunity against a selected pathogen in a subject. The present invention discloses the use of skin application in combination with conventional vaccination or priming for improved immunization or vaccination of a subject against a selected pathogen.

Abstract: The invention relates to a patch for cutaneous application of a substance, the patch comprising a substance designed to penetrate the epidermis, means for placing the substance in contact with the skin and a peelable cutaneous exfoliation film enabling exfoliation of the skin, after placing the patch, at the level of the contact zone between said substance and the skin.

Abstract: The present invention describes a new method for progressive desensitization of a subject to groundnut. More specifically, the invention relates to the immunotherapeutic method for increasing groundnut tolerance in an allergic subject using epicutaneous administration. The present invention is also relative to the use of a skin patch device for progressive desensitization of a subject to groundnut.

Abstract: A patch comprises a support having electrostatic properties. The periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is directly covered with at least one biologically active substance in the form of particles. The particles remain in contact with the non-adhesive part of the support as a result of the electrostatic forces.

Abstract: The invention relates to a patch for cutaneous application of a substance, the patch comprising a substance designed to penetrate the epidermis, means for placing the substance in contact with the skin and a peelable cutaneous exfoliation film enabling exfoliation of the skin, after placing the patch, at the level of the contact zone between said substance and the skin.

Abstract: A patch comprising a support having electrostatic properties is provided wherein a periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is covered with at least one biologically active substance in the form of particles that is adhered to the non-adhesive part of the support by electrostatic forces.

Abstract: A dermal patch comprises a support having electrostatic properties, which is covered with or can be covered with a substance that is intended to be applied to the skin. The surface of the support that is in contact with the substance is provided with microreliefs.

Abstract: A patch comprising a support having electrostatic properties is provided wherein a periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is covered with at least one biologically active substance in the form of particles that is adhered to the non-adhesive part of the support by electrostatic forces.

Abstract: A patch comprises a support having electrostatic properties. The periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is directly covered with at least one biologically active substance in the form of particles. The particles remain in contact with the non-adhesive part of the support as a result of the electrostatic forces.