Abstract: Disclosed herein are artificially synthesized nucleic acid constructs to guide an epigenetic modification for at least partially silencing or activating a target gene in an organism such as a plant or seed, and formulations thereof. Also disclosed are methods of applying such nucleic acid constructs to the plant or to the seed. Also disclosed are engineered seeds and plants obtained by the epigenetic modification.
Type:
Grant
Filed:
February 15, 2023
Date of Patent:
January 21, 2025
Assignee:
DECIBEL BIO, INC
Inventors:
Travis Bayer, Kevin L. Schneider, Aden Kinne, Jennifer Adele Samson, Itxaso Garay