Patents Assigned to deCODE Chemistry, Inc.
  • 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY
    Publication number: 20090042900
    Abstract: 2,4-Diaminoquinazolines of formula (I) are provided herein and are useful for treating spinal muscular atrophy (SMA).
    Type: Application
    Filed: August 1, 2007
    Publication date: February 12, 2009
    Applicant: DECODE CHEMISTRY, INC.
    Inventors: Jasbir Singh, Mark Gurney
  • BIARYL NITROGEN-HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070149544
    Abstract: The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: August 3, 2006
    Publication date: June 28, 2007
    Applicant: DECODE CHEMISTRY, INC.
    Inventors: Vincent SANDANAYAKA, Jasbir SINGH, Li-Ming ZHOU, Mark E. GURNEY
  • BIARYL SUBSTITUTED NITROGEN CONTAINING HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070142432
    Abstract: The present invention relates to a chemical genus of biaryl substituted nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: August 3, 2006
    Publication date: June 21, 2007
    Applicant: deCODE Chemistry, Inc.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Mahnaz Keyvan, Michael David Krohn, Mark E. Gurney
  • N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070142434
    Abstract: The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: August 3, 2006
    Publication date: June 21, 2007
    Applicant: DECODE CHEMISTRY, INC.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Lei Zhao, Mark E. Gurney
  • BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070078263
    Abstract: The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: June 23, 2006
    Publication date: April 5, 2007
    Applicant: deCODE Chemistry, Inc.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Mark Gurney, Bjorn Mamat, Peng Yu, Louis Bedell, Lei Zhao
  • BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070066820
    Abstract: The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: June 23, 2006
    Publication date: March 22, 2007
    Applicant: DECODE CHEMISTRY, INC.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Mark Gurney, Bjorn Mamat, Peng Yu, Louis Bedel, Lei Zhao
  • Carboxylic acid peri-substituted bicyclics for occlusive artery disease
    Publication number: 20060142355
    Abstract: Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 29, 2006
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney, Georgeta Hategan, Peng Yu, David Zembower, Nian Zhou, Alexandre Polozov, Wayne Zeller
  • Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease
    Publication number: 20060142348
    Abstract: Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 29, 2006
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney, Georgeta Hategan
  • 2,4-diaminoquinazolines for spinal muscular atrophy
    Publication number: 20050288314
    Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).
    Type: Application
    Filed: June 7, 2005
    Publication date: December 29, 2005
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney