Patents Assigned to deCODE Chemistry, Inc.
  • BIARYL SUBSTITUTED NITROGEN CONTAINING HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070142432
    Abstract: The present invention relates to a chemical genus of biaryl substituted nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: August 3, 2006
    Publication date: June 21, 2007
    Applicant: deCODE Chemistry, Inc.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Mahnaz Keyvan, Michael David Krohn, Mark E. Gurney
  • BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
    Publication number: 20070078263
    Abstract: The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
    Type: Application
    Filed: June 23, 2006
    Publication date: April 5, 2007
    Applicant: deCODE Chemistry, Inc.
    Inventors: Vincent Sandanayaka, Jasbir Singh, Mark Gurney, Bjorn Mamat, Peng Yu, Louis Bedell, Lei Zhao
  • Carboxylic acid peri-substituted bicyclics for occlusive artery disease
    Publication number: 20060142355
    Abstract: Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 29, 2006
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney, Georgeta Hategan, Peng Yu, David Zembower, Nian Zhou, Alexandre Polozov, Wayne Zeller
  • Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease
    Publication number: 20060142348
    Abstract: Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 29, 2006
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney, Georgeta Hategan
  • 2,4-diaminoquinazolines for spinal muscular atrophy
    Publication number: 20050288314
    Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).
    Type: Application
    Filed: June 7, 2005
    Publication date: December 29, 2005
    Applicant: deCODE Chemistry, Inc.
    Inventors: Jasbir Singh, Mark Gurney