Patents Assigned to DEFENCE THE SECRETARY OF STATE FOR DSTL, PORTON DOWN
  • Francisella Strain for Live Vaccine
    Publication number: 20070264233
    Abstract: A strain of Francisella species wherein a gene which encodes an enzyme in the purine pathway has been inactivated, and which is able to produce a protective immune response in an animal, for use as a live prophylactic or therapeutic vaccine against infection by said Francisella species. Suitable genes for inactivation include the purF gene. Pharmaceutical compositions and methods which utilise these strains are also described and claimed.
    Type: Application
    Filed: March 24, 2005
    Publication date: November 15, 2007
    Applicant: DEFENCE THE SECRETARY OF STATE FOR DSTL, PORTON DOWN
    Inventors: Stephen Lloyd Michell, Petra Oyston, Janine Quarry, Richard Titball