Abstract: The present invention relates to methods for treatment or prevention of liver, biliary tract, and pancreatic disorders by administering one or more defensins. Included within the scope of the disclosure is also treatment of certain metabolic disorders.
Abstract: Treatment of an inflammatory bowel disease in a subject in need thereof by simultaneous or successive parenteral and oral administration of a mammalian beta defensin is described. Oral administration of mammalian beta defensin to a subject during remission to keep said subject suffering from IBD in remission, prolong remission in said subject suffering from IBD, to reduce the occurrence of relapse in said subject suffering from IBD, or any combination thereof, is also described.
Type:
Grant
Filed:
November 16, 2015
Date of Patent:
December 5, 2017
Assignee:
Defensin Therapeutics ApS
Inventors:
Tanja Maria Rosenkilde Kjær, Birgitte Andersen, Karoline Sidelmann Brinch
Abstract: Treatment of an inflammatory bowel disease in a subject in need thereof by simultaneous or successive parenteral and oral administration of a mammalian beta defensin is described. Oral administration of mammalian beta defensin to a subject during remission to keep said subject suffering from IBD in remission, prolong remission in said subject suffering from IBD, to reduce the occurrence of relapse in said subject suffering from IBD, or any combination thereof, is also described.
Type:
Grant
Filed:
July 5, 2012
Date of Patent:
December 22, 2015
Assignee:
Defensin Therapeutics ApS
Inventors:
Tanja Maria Rosenkilde Kjær, Birgitte Andersen, Karoline Sidelmann Brinch