Abstract: This disclosure relates to an amyloid beta peptide (A?)-oligomer-specific antigen binding molecule and the use thereof as a diagnostic agent or as a therapeutic agent for the treatment or prevention of Alzheimer's Disease, Down's syndrome, mild cognitive impairment, cerebral amyloid angiopathy, vascular dementia, multi-infarct dementia, Parkinson's disease, Dementia with Lewy Bodies, Huntington's disease, Creutzfeldt-Jakob disease, cystic fibrosis, or Gaucher's disease.
Type:
Grant
Filed:
November 7, 2017
Date of Patent:
August 31, 2021
Assignee:
DegenRx B.V.
Inventors:
Samantha Kathleen Cobb, Michael Foley, Augustinus Petrus Henricus Scheefhals, Armand Wilbrandt Jannes Wichert Tepper