Abstract: The invention relates to a process comprising the following process steps: a) introducing an ethylenically unsaturated compound; b) adding a monophosphine ligand and a compound which comprises Pd, or adding a complex comprising Pd and a monophosphine ligand; c) adding an aliphatic alcohol; d) supplying CO; e) heating the reaction mixture, the ethylenically unsaturated compound being reacted to form an ester; where the monophosphine ligand is a compound of formula (I) where R1 is selected from —(C1-C12)-alkyl, —O—(C1-C12)-alkyl, —O—(C6-C20)-aryl, —(C6-C20)-aryl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —(C3-C20)-heteroaryl; R2 is selected from —(C6-C20)-aryl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —(C3-C20)-heteroaryl; R3 is —(C3-C20)-heteroaryl; and R1, R2 and R3 may each independently be substituted by one or more substituents selected from —(C1-C12)-alkyl, —(C3-C12)-cycloalkyl, —(C3-C12)-heterocycloalkyl, —O—(C1-C12)-alkyl, —O—(C1-C12)-alkyl-(C6-C20)-aryl, —O—(C3-C12)-cyclo
Type:
Grant
Filed:
July 14, 2017
Date of Patent:
January 28, 2020
Assignee:
EVONIK DEGUSSA GMBH
Inventors:
Kaiwu Dong, Ralph Jackstell, Matthias Beller, Dirk Fridag, Dieter Hess, Katrin Marie Dyballa, Frank Geilen, Robert Franke
Abstract: Provided is a method of producing at least one omega-hydroxyl fatty acid, the method comprising: (a) contacting at least one alkane with at least one recombinant yeast cell in an aqueous medium, wherein the yeast cell is capable of oxidising the alkane to the corresponding omega-hydroxyl fatty acid and the yeast cell comprises a reduced fatty acid degradation capacity.
Type:
Application
Filed:
July 26, 2017
Publication date:
January 23, 2020
Applicant:
Evonik Degussa GmbH
Inventors:
Thomas HAAS, Markus POTTER, Li LI, Guoqing TAO, Dong CAO
Abstract: Disclosed herein is a cell culture media containing L-glutamine from a set of N-acylated dipeptides Acyl-X-Q, and L-glutamine from a set of other glutamine-sources Qsource in a defined molar ratio R=n(Acyl-X-Q)/n(Qsource), wherein the variables X, Q, Acyl, R, n(Acyl-X-Q) and n(Qsource) are defined in the general disclosure. Processes of using the cell culture media are also described herein.
Abstract: A novel method is for the fermentative production of L-lysine using bacteria of the species Corynebacterium glulamicum. The bacteria have the ability to excrete L-lysine and contain in their chromosome a polynucleotide, which encodes a polypeptide having the activity of a transcriptional factor. An amino acid at a particular position of the amino acid sequence of the polypeptide has been substituted by a different proteinogenic amino acid.
Type:
Application
Filed:
July 10, 2019
Publication date:
January 16, 2020
Applicant:
Evonik Degussa GmbH
Inventors:
Thomas BEKEL, Frank Schneider, Georg Thierbach, Kornelia Voß
Abstract: The present invention relates to production processes for reactive monomer species. The method described herein may be used in a variety of reactive monomer production processes to optimize the use of polymerization inhibitor compounds, which may lead to further advantages such as debottlenecking or elimination of process plant separation unit(s). The method provides for the separation of oligomeric/polymeric species, inhibitor compounds and reactive monomer, optionally in the presence of unreacted raw materials or solvent(s), within the production process by means of membrane filtration, particularly through the use of solvent stable membranes, and in particular by applying organic solvent nanofiltration membranes.
Type:
Grant
Filed:
September 22, 2015
Date of Patent:
January 14, 2020
Assignee:
Evonik Degussa GmbH
Inventors:
Andrew Boam, Yuri Bouwhuis, Phillip R. James, Velichka Yordanova Koleva, Felix Nissen
Abstract: The present invention relates to polynucleotides encoding novel fusion polypeptides essentially composed of a signal peptide for membrane translocation and a polypeptide providing ?-1,6-glucosidase activity and to bacteria containing said polynucleotides. The invention further relates to methods for producing fine chemicals using media containing isomaltose and/or panose as carbon source.
Type:
Grant
Filed:
June 13, 2018
Date of Patent:
January 14, 2020
Assignee:
Evonik Degussa GmbH
Inventors:
Kornelia Voss, Michaela Voss, Georg Thierbach
Abstract: It has been found according to the invention, that a biomass containing an oxidation-sensitive material of value may be dried under particularly mild conditions by a method in which the drying gas is passed over the biomass to be dried in cycle gas mode.
Type:
Grant
Filed:
July 8, 2014
Date of Patent:
January 14, 2020
Assignee:
Evonik Degussa, GmbH
Inventors:
Nicolas Rudinger, Christian Rabe, Wilfried Blümke
Abstract: The present invention relates to a culture medium, preferably a cell culture medium, comprising at least one dipeptide, the dipeptide comprising asparagine (Asn) and glutamine (Gln). The invention further relates to the use of a culture medium of the invention for culturing cells, preferably plant cells, animal cells or mammalian cells. Another aspect of the invention relates to a method of manufacturing a cell culture product comprising the steps of (i) providing a cell capable of producing said cell culture product; (ii) contacting said cell with a culture medium according to the invention; and (iii) obtaining said cell culture product from said culture medium or from said cell.
Type:
Application
Filed:
March 2, 2018
Publication date:
January 9, 2020
Applicant:
Evonik Degussa GmbH
Inventors:
Friedhelm MERZ, Andreas KARAU, Thomas HERMANN, Guenter KNAUP
Abstract: Process for producing coated mixed lithium oxide particles, in which mixed lithium oxide particles and a mixture comprising aluminium oxide and titanium dioxide are subjected to dry mixing by means of a mixing unit having a specific power of 0.1-1 kW per kg of mixed lithium oxide particles and mixture used, in total, under shearing conditions. Coated mixed lithium oxide particles comprising a mixture of aluminium oxide and titanium dioxide as coating material, wherein the aluminium oxide and the titanium dioxide are in the form of aggregated primary particles and the weight ratio of aluminium oxide to titanium dioxide is 10:90-90:10.
Abstract: A process produces a C3- to C20-alkyltrialkoxysilane by hydrosilylation, wherein alkoxy represents methoxy, ethoxy or propoxy. Initially, a mixture is charged of at least one hydroalkoxysilane from the group of hydrotrialkoxysilane, hydroalkyldialkoxysilane, and hydrodialkylalkoxysilane, and a Pt catalyst. The mixture is then heated to a temperature of 30° C. to 60° C. Subsequently, with mixing, an omega-unsaturated or mono-unsaturated C3- to C20-hydrocarbon, at least one carboxylic acid and at least one alcohol as cocatalysts are added to the mixture. The mixture is then reacted and subsequently worked up to obtain the product.
Abstract: A process for preparing SiC-bonded polyethersiloxanes by precious metal-catalysed addition of olefinically unsaturated polyethers onto siloxanes having SiH groups is described, wherein, prior to commencement of reaction, the siloxane having SiH groups is mixed with an olefinically unsaturated polyether and with a polyethersiloxane by stirring, and then contacted with a precious metal catalyst and optionally further additives, and the SiC bond formation reaction is conducted up to an SiH conversion, determined by gas-volumetric means, of at least 97%.
Abstract: The invention relates to bisphosphites having 2,4-tert-butylphenyl units and a method for the preparation thereof. Furthermore, the invention relates to the use of the compounds as ligands in a ligand-metal complex. The compound, and also the complex, may be used as a catalytically active composition in hydroformylation reactions.
Type:
Grant
Filed:
November 7, 2017
Date of Patent:
January 7, 2020
Assignee:
EVONIK DEGUSSA GMBH
Inventors:
Katrin Marie Dyballa, Robert Franke, Dirk Fridag, Dieter Hess
Abstract: A process for preparing SiC-bonded polyethersiloxanes by precious metal-catalysed addition of olefinically unsaturated polyethers onto siloxanes having SiH groups is described, in which, prior to commencement of reaction, the siloxane having SiH groups is mixed together with a polyethersiloxane, preferably by stirring, and then, in a second step, this preliminary mixture is contacted with an olefinically unsaturated polyether and with a precious metal catalyst and optionally further additives, preferably with further stirring, and the SiC bond formation reaction is conducted up to an SiH conversion, determined by gas-volumetric means, of at least 97%.
Abstract: The present invention relates to a process for hydrogenating nitrile compounds to amino compounds, in which the cross-sectional loading of the reactor during the hydrogenation is less than or equal to 4.0 kg/m2*s, based on the liquid phase.
Type:
Grant
Filed:
May 17, 2018
Date of Patent:
December 31, 2019
Assignee:
Evonik Degussa GmbH
Inventors:
Anne Rittsteiger, Stephan Kohlstruk, Dirk Hoppe, Alexander Martin Rüfer, Sabrina Sowka, Sven Schneider, Norbert Schlüter, Axel Hengstermann, Markus Galle, Stefan Röder, Monika Berweiler
Abstract: The invention relates to a culture medium containing at least one oligopeptide of 2-10 amino acids in length. The amino acids are natural amino acids. At least one of the amino acids is lysine; and one further is cysteine, cystine, leucine, tyrosine, valine, or Isoleucine. The oligopeptide is present in an amount of at least 0.1 mM. The invention also relates to the use of the culture medium for culturing cells, preferably plant cells, animal cells or mammalian cells. The invention further relates to a method of manufacturing a cell culture product including the steps of (i) providing a cell capable of producing the cell culture product; (ii) contacting the cell with the culture medium, and (iii) obtaining the cell culture product from the culture medium or from the cell.
Type:
Application
Filed:
March 2, 2018
Publication date:
December 26, 2019
Applicant:
Evonik Degussa GmbH
Inventors:
Guenter KNAUP, Friedhelm MERZ, Christian KESSLER
Abstract: The invention relates to a process for dehumidifying a moist gas mixture. The invention further relates to an apparatus for dehumidifying a moist gas mixture and to the use of said apparatus in the process according to the invention.
Type:
Grant
Filed:
June 12, 2017
Date of Patent:
December 24, 2019
Assignee:
Evonik Degussa GmbH
Inventors:
Olivier Zehnacker, Benjamin Willy, Xinming Wang, Rolf Schneider
Abstract: The invention relates to a process for dehumidifying a moist gas mixture. The invention further relates to an apparatus for dehumidifying a moist gas mixture and to the use of said apparatus in the process according to the invention.
Type:
Grant
Filed:
June 12, 2017
Date of Patent:
December 24, 2019
Assignee:
Evonik Degussa GmbH
Inventors:
Olivier Zehnacker, Benjamin Willy, Xinming Wang, Rolf Schneider
Abstract: Process for the simple and practical application of a relatively thick heat-insulating layer to a surface to be insulated by: (a) applying a porous substrate consisting of a spacer fabric to the surface of an article, which surface is to be insulated; (b) filling the porous substrate with a heat-insulating formulation; (c) curing the formulation filled into the porous substrate.