Patents Assigned to DEKK-TEC, Inc.
-
Publication number: 20200375964Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: ApplicationFiled: August 17, 2020Publication date: December 3, 2020Applicant: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 10772878Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: GrantFiled: December 29, 2017Date of Patent: September 15, 2020Assignee: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Publication number: 20180117022Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: ApplicationFiled: December 29, 2017Publication date: May 3, 2018Applicant: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 9884051Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: GrantFiled: August 16, 2016Date of Patent: February 6, 2018Assignee: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Publication number: 20160354354Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: ApplicationFiled: August 16, 2016Publication date: December 8, 2016Applicant: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 9422241Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders.Type: GrantFiled: February 22, 2012Date of Patent: August 23, 2016Assignee: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 8795659Abstract: The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula I: (I) wherein A+ represents an ammonium species selected from the protonated (conjugate acid) or quaternary forms of aliphatic amines and aromatic amines, including basic amino acids, heterocyclic amines, substituted and unsubstituted pyridines, guanidines and amidines; and X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: GrantFiled: July 3, 2012Date of Patent: August 5, 2014Assignee: Dekk-Tec, Inc.Inventor: Lee R. Morgan
-
Patent number: 8361992Abstract: The present disclosure concerns complexes of 4-hydroperoxy ifosfamide. In one embodiment the complexes can be represented by the formula wherein A represents an ammonium species selected from the conjugate acid of a basic amino acid, quaternary ammonium, aliphatic ammonium, heterocyclic ammonium, aromatic ammonium, substituted and unsubstituted pyridinium, guanidinium, and amidinium, and wherein X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: GrantFiled: February 24, 2010Date of Patent: January 29, 2013Assignee: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 8232262Abstract: The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula wherein A+ represents an ammonium species selected from the protonated (conjugate acid) or quaternary forms of aliphatic amines and aromatic amines, including basic amino acids, heterocyclic amines, substituted and unsubstituted pyridines, guanidines and amidines; and X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: GrantFiled: October 25, 2005Date of Patent: July 31, 2012Assignee: DEKK-TEC, Inc.Inventor: Lee Roy Morgan
-
Patent number: 8124596Abstract: This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one embodiment the analogs are represented by the formula (1).Type: GrantFiled: December 12, 2006Date of Patent: February 28, 2012Assignee: Dekk-Tec, Inc.Inventor: Lee Roy Morgan
-
Patent number: 7678778Abstract: The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula wherein A+ represents an ammonium species selected from the protonated (conjugate acid) or quaternary forms of aliphatic amines and aromatic amines, including basic amino acids, heterocyclic amines, substituted and unsubstituted pyridines, guanidines and amidines; and X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: GrantFiled: October 25, 2005Date of Patent: March 16, 2010Assignee: DEKK-TEC, Inc.Inventor: Lee Roy Morgan
-
Publication number: 20080267945Abstract: The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula wherein A+ represents an ammonium species selected from the protonated (conjugate acid) or quaternary forms of aliphatic amines and aromatic amines, including basic amino acids, heterocyclic amines, substituted and unsubstituted pyridines, guanidines and amidines; and X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: ApplicationFiled: October 25, 2005Publication date: October 30, 2008Applicant: Dekk-TEC, IncInventor: Lee Roy Morgan
-
Publication number: 20060089333Abstract: The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula wherein A+ represents an ammonium species selected from the protonated (conjugate acid) or quaternary forms of aliphatic amines and aromatic amines, including basic amino acids, heterocyclic amines, substituted and unsubstituted pyridines, guanidines and amidines; and X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds and formulating pharmaceutical compositions thereof. Methods for administering the disclosed compounds to subjects, particularly to treat hyperproliferative disorders, also are disclosed.Type: ApplicationFiled: October 25, 2005Publication date: April 27, 2006Applicant: Dekk-TEC Inc.Inventor: Lee Morgan