Patents Assigned to Delineate
  • Microparticles as ultrasonic contrast media
    Patent number: 5333613
    Abstract: Ultrasonic contrast media are provided comprising small particles with entrapped gas, where the compositions can be selected for rapid dissolution with production of microbubbles or maintaining the gas in microtubules, microchambers or microcracks, providing for echogenicity. The particles are readily formed by precipitation from a liquid, either solution or melt, of a monomeric material, followed by drying and mechanically reducing the size of the particles.
    Type: Grant
    Filed: March 23, 1993
    Date of Patent: August 2, 1994
    Assignee: Delineate
    Inventors: Ernest G. Tickner, Robert E. Short, David H. Rammler