Patents Assigned to DELL' IMMACOLATA CONCEZIONE-ISTITUTO DERMOOPATICO DELL' IMMACOLATA
  • Peptide inhibiting platelet derived growth factor (PDGF-BB) and fibroblast growth factor (bFGF) activity
    Publication number: 20060014693
    Abstract: A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. Said molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC). Said molecule is also able to inhibit in vivo angiogenesis CD1 mice.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 19, 2006
    Applicants: DELL' IMMACOLATA CONCEZIONE-ISTITUTO DERMOOPATICO DELL' IMMACOLATA
    Inventors: Antonio Facchiano, Francesco Facchiano, Angelo Facchiano