Patents Assigned to DELPHI GENETICS
  • Host cell for producing proteins
    Patent number: 10718001
    Abstract: Disclosed is a host cell for producing a recombinant peptide, polypeptide or protein of interest, wherein the host cell includes at least 2 copies of a nucleic acid sequence encoding a poison protein; and to the use thereof for producing peptides, polypeptides or proteins of interest.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: July 21, 2020
    Assignee: DELPHI GENETICS
    Inventors: Cedric Szpirer, Jonathan Cavrenne, Benjamin Michel
  • Genetically modified phage and use thereof
    Patent number: 9920323
    Abstract: The present invention relates to a genetically modified phage and use thereof in a method for producing a biomolecule of interest.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: March 20, 2018
    Assignee: DELPHI GENETICS
    Inventor: Cedric Szpirer
  • Method for producing antibody using “naked” expression vector expressing type II transmembrane fusion protein
    Patent number: 9234042
    Abstract: Methods are disclosed for generating antibodies and an expression vector used to express protein(s) which provoke the antibody response. The expression vector may be useful in generating an antibody directed to an antigen, comprising a gene in operable linkage with a promoter, which gene encodes upon expressing a fusion protein comprising (i) CD134L, a fragment or homologous protein thereof as N-terminal moiety of the fusion protein; and (ii) all or part of an antigenic protein as C-terminal moiety of the fusion protein. To generate the antibodies, the vector is injected into a subject animal, which produces a fusion protein, against which antibodies are generated.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: January 12, 2016
    Assignee: DELPHI GENETICS SA
    Inventors: Jean-Christophe Renauld, Muriel Lemaire, Laurie Dumoutier, Yannick Nizet, Alain Vanderplasschen, Laurent Gillet
  • GENETICALLY MODIFIED PHAGE AND USE THEREOF
    Publication number: 20140147890
    Abstract: The present invention relates to a genetically modified phage and use thereof in a method for producing a bio molecule of interest.
    Type: Application
    Filed: July 6, 2012
    Publication date: May 29, 2014
    Applicant: DELPHI GENETICS
    Inventor: Cedric Szpirer
  • Genetically Modified Phage and Use Thereof
    Publication number: 20130011898
    Abstract: The present invention relates to a genetically modified phage and use thereof in a method for producing a biomolecule of interest.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 10, 2013
    Applicant: DELPHI GENETICS
    Inventor: Cédric Szpirer
  • METHOD FOR PRODUCING ANTIBODY USING "NAKED" EXPRESSION VECTOR EXPRESSING TYPE II TRANSMEMBRANE FUSION PROTEIN
    Publication number: 20120093825
    Abstract: Methods are disclosed for generating antibodies and an expression vector used to express protein(s) which provoke the antibody response. The expression vector may be useful in generating an antibody directed to an antigen, comprising a gene in operable linkage with a promoter, which gene encodes upon expressing a fusion protein comprising (i) CD134L, a fragment or homologous protein thereof as N-terminal moiety of the fusion protein; and (ii) all or part of an antigenic protein as C-terminal moiety of the fusion protein. To generate the antibodies, the vector is injected into a subject animal, which produces a fusion protein, against which antibodies are generated.
    Type: Application
    Filed: October 18, 2011
    Publication date: April 19, 2012
    Applicant: DELPHI GENETICS SA
    Inventors: JEAN-CHRISTOPHE RENAULD, MURIEL LEMAIRE, LAURIE DUMOUTIER, YANNICK NIZET, ALAIN VANDERPLASSCHEN, LAURENT GILLET