Abstract: The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
Type:
Grant
Filed:
February 3, 2017
Date of Patent:
November 14, 2017
Assignee:
Denali Therapeutics Inc.
Inventors:
Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Colin Philip Leslie, Joseph P. Lyssikatos, Alfonso Pozzan, Zachary K. Sweeney, Javier de Vicente Fidalgo
Abstract: The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
October 31, 2017
Assignee:
DENALI THERAPEUTICS, INC.
Inventors:
Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
Abstract: The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.
Type:
Grant
Filed:
July 15, 2016
Date of Patent:
September 26, 2017
Assignee:
DENALI THERAPEUTICS, INC.
Inventors:
Duane A. Burnett, Matthew Gregory Bursavich, Andrew J. McRiner