Patents Assigned to Denervx LLC
  • Patent number: 10390881
    Abstract: A catheter is disclosed for creating a lesion in nerve-containing tissue spaced from a body lumen while protecting tissue forming and adjacent to a wall of the body lumen from injury. The catheter includes a catheter body having at least one fluid passage therein, a balloon in communication with the at least one fluid passage to receive cooling fluid for inflating the balloon, a microwave antenna carried by the catheter that emits microwave energy omnidirectionally, thereby heating the tissue spaced from the body lumen to a temperature sufficient to cause thermal damage while the tissue forming and adjacent to the wall of the body lumen are maintained at a temperature where thermal damage does not occur, and a tip structure located at an end of the catheter body, configured to receive a guide wire extending through the at least one fluid passage in the catheter body.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: August 27, 2019
    Assignee: Denervx LLC
    Inventor: Eric N. Rudie
  • Patent number: 10179029
    Abstract: A method of performing denervation with a cooled microwave denervation catheter assembly includes advancing a catheter body over a guide wire in a body lumen of a patient to a treatment location adjacent targeted nerves, with the guide wire being located in an interior lumen of the catheter body, inflating the balloon with cooling fluid to contact a wall of the body lumen of the patient, removing the guide wire from the interior lumen of the catheter body, and inserting a microwave antenna catheter into the interior lumen of the catheter body, so that denervation treatment may be performed by simultaneously circulating cooling fluid in the balloon and supplying power to the microwave antenna, to cause the targeted nerves to be heated to a temperature sufficient to cause thermal damage while the wall of the body lumen is maintained at a temperature where thermal damage does not occur.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: January 15, 2019
    Assignee: Denervx LLC
    Inventors: Eric N. Rudie, Philip J. Haarstad, Stanley E. Kluge
  • Patent number: 10092352
    Abstract: A device and method is disclosed for creating a lesion in adventitia tissue of a renal artery and/or a region of tissue surrounding the adventitia tissue while protecting intima and media tissue of the renal artery from injury. A catheter carrying a microwave antenna is positioned within the renal artery. Cooling fluid is circulated around the microwave antenna in thermal contact with the intima of the renal artery. Power is supplied to the microwave antenna to cause microwave energy to be emitted omnidirectionally from the microwave antenna. The power supplied to the microwave antenna and the cooling fluid circulated around the microwave antenna are controlled to cause the adventitia tissue and/or the region of tissue surrounding the adventitia tissue to be heated to a temperature sufficient to cause thermal damage while the intima and media tissue are maintained at a temperature where thermal damage does not occur.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: October 9, 2018
    Assignee: Denervx LLC
    Inventor: Eric N. Rudie
  • Patent number: 9333035
    Abstract: A device and method is disclosed for creating a lesion in adventitia tissue of a renal artery and/or a region of tissue surrounding the adventitia tissue while protecting intima and media tissue of the renal artery from injury. A catheter carrying a microwave antenna is positioned within the renal artery. Cooling fluid is circulated around the microwave antenna in thermal contact with the intima of the renal artery. Power is supplied to the microwave antenna to cause microwave energy to be emitted omnidirectionally from the microwave antenna. The power supplied to the microwave antenna and the cooling fluid circulated around the microwave antenna are controlled to cause the adventitia tissue and/or the region of tissue surrounding the adventitia tissue to be heated to a temperature sufficient to cause thermal damage while the intima and media tissue are maintained at a temperature where thermal damage does not occur.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: May 10, 2016
    Assignee: Denervx LLC
    Inventor: Eric N. Rudie
  • Publication number: 20140081254
    Abstract: A device and method is disclosed for creating a lesion in adventitia tissue of a renal artery and/or a region of tissue surrounding the adventitia tissue while protecting intima and media tissue of the renal artery from injury. A catheter carrying a microwave antenna is positioned within the renal artery. Cooling fluid is circulated around the microwave antenna in thermal contact with the intima of the renal artery. Power is supplied to the microwave antenna to cause microwave energy to be emitted omnidirectionally from the microwave antenna. The power supplied to the microwave antenna and the cooling fluid circulated around the microwave antenna are controlled to cause the adventitia tissue and/or the region of tissue surrounding the adventitia tissue to be heated to a temperature sufficient to cause thermal damage while the intima and media tissue are maintained at a temperature where thermal damage does not occur.
    Type: Application
    Filed: September 19, 2013
    Publication date: March 20, 2014
    Applicant: Denervx LLC
    Inventor: Eric N. Rudie