Patents Assigned to DENTOGNOSTICS GMBH
  • MMP-8 activation product, its determination and use
    Patent number: 11378579
    Abstract: The present invention relates to a novel MMP-8 activation product such as a MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: July 5, 2022
    Assignees: Oy Medix Biochemica AB, Dentognostics GmbH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Païvi Mäntylä, Ismo Råman, Sinikka Tiisala
  • MMP-8 activation product, its determination and use
    Patent number: 10488415
    Abstract: MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 26, 2019
    Assignees: OY MEDIX BIOCHEMICA AB, DENTOGNOSTICS GMBH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Päivi Mäntylä, Ismo Råman, Sinikka Tiisala
  • MMP-8 activation product, its determination and use
    Patent number: 10330681
    Abstract: MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 25, 2019
    Assignees: OY MEDIX BIOCHEMICA AB, DENTOGNOSTICS GMBH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Päivi Mäntylä, Ismo Råman, Sinikka Tiisala
  • PROCESS FOR AVOIDING FALSE POSITIVE RESULTS IN A DETECTING PROCESS OF AN INFLAMMATION INDICATOR IN A RINSE SOLUTION FOR TAKING UP GINGIVAL CREVICULAR FLUID
    Publication number: 20130217034
    Abstract: A process for avoiding false positive results in a detecting process of an inflammation indicator from the matrix metalloproteinase (MMP) family in a gingival crevicular fluid (GCF), wherein said GCF, which is obtained from a mouthrinse or saliva, is filtered before said inflammation indicator from the MMP family is assayed.
    Type: Application
    Filed: August 12, 2011
    Publication date: August 22, 2013
    Applicant: DENTOGNOSTICS GMBH
    Inventors: Kurt Maier, Timo Sorsa