Abstract: A pressure differential sampling and filtering device and method comprising a tube adapted to hold a liquid to be filtered and an inner tube having a filter head adapted to be inserted into the tube and force the liquid up through the filter head into the inner tube is characterized by the employment of a filter head and by the inner tube being associated with and separable from a closed-end portion which then serves as a test tube when the assembly is inverted and the filter head separated therefrom.

Abstract: Microliter sized samples of filtered urine or the like are obtained by taking up a few drops of urine into a bulb-type micro-syringe inserting the nozzle thereof tightly into the inlet passageway of a micro-filter having a disc of filter paper as the filtering medium held firmly between the inlet passageway and an outlet passageway and squeezing the bulb of the micro-syringe to force the urine through the filter paper. The outlet passageway is constricted in size and shape to discharge the filtered urine in drops. The filtered urine then comes through in uniform drops of predetermined size which are utilized in a testing procedure, for example, in a direct agglutination test for pregnancy.