Patents Assigned to DEO Corporation
  • Composition for treating dry eye
    Patent number: 6254893
    Abstract: A calcium-based ophthalmic composition for treating dry eye including a hydrophobic carrier, such as petrolatum, and a calcium salt. Also a method for treating dry eye comprising the step of administering the composition according to the present invention.
    Type: Grant
    Filed: October 23, 1998
    Date of Patent: July 3, 2001
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen
  • Composition for treating dry eye
    Patent number: 5830508
    Abstract: A calcium-based ophthalmic composition for treating dry eye is disclosed. The composition includes a hydrophobic carrier such as petrolatum and a calcium salt. The composition can further include a polyol such as glycerol, and an agent such as anhydrous lanolin, to enhance the interface between the carrier, and the calcium salt and polyol. Also disclosed is a method for treating dry eye comprising the step of administering the composition according to the present invention by placing the composition on the lateral portion of the lower eyelid margin. This method allows the composition to gradually disperse onto the cornea and conjunctiva.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 3, 1998
    Assignee: Deo Corporation
    Inventor: Donald L. MacKeen
  • Ophthalmic composition for treating dry eye
    Patent number: 5595764
    Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: January 21, 1997
    Assignee: DEO Corporation
    Inventor: Donald L. Mackeen
  • Method of ophthalmic drug delivery
    Patent number: 5366739
    Abstract: A method for prolonged delivery of a therapeutic agent to the eye is disclosed. The method provides for the addition of a desired drug to a suitable, preferably non-aqueous, vehicle. An amount of the vehicle containing a therapeutic dose of the drug is placed on the extraocular skin adjacent to the lateral canthus of the eye. Movements of the orbicularis oculi associated with the scissor-like closing of the lids of the eye continuously transport small portions of the drug containing vehicle into the interpalpebral space where the drug is released to the cornea for intraocular penetration and treatment effected. The method of the invention is particularly effective in delivering insoluble calcium salts for the treatment of dry eye.
    Type: Grant
    Filed: December 19, 1992
    Date of Patent: November 22, 1994
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen
  • Opthalmic composition for treating dry eye
    Patent number: 5290572
    Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: March 1, 1994
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen