Abstract: Methods and devices are provided for attaching soft tissue to bone. In general, a deployment device, insertion assembly, and suture anchor are provided. The insertion assembly is coupled between the deployment device and the suture anchor to allow the deployment device to deploy the suture anchor into bone. Each of the various components disclosed herein can be used alone, in combination with one another, or in combination with various other devices.

Abstract: A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel.

Abstract: A bioimplantable tissue fixation device is provided for use in repairing and replacing torn or damaged connective tissue such as ligaments and tendons. The device includes an elongate body formed of a bioresorbable material including an outer surface, a proximal end, a distal end and a longitudinal axis extending therethrough. The body includes an internal cavity open at the proximal end which terminates proximal to the distal end. The internal cavity is in fluid communication with at least one opening formed in the outer surface of the body. The internal cavity is able to accept a treatment material for delivery external to the outer surface of the body through the at least one opening at the proximal end.

Abstract: A suturing apparatus comprises a pair of jaws. A bendable needle housed in one of the jaws is adapted to carry a suture. An optional suture receiver may be disposed adjacent to the opposite jaw. A transition block curves the needle and directs it in a direction generally unparallel to an axis of the carrying jaw. The needle may also be configured to retrieve a suture. A retaining mechanism holds a suture in place to be engaged by the needle. The jaw housing the needle may include a lateral opening through which the suture may be inserted. The needle may also include a lateral notch which may be aligned with lateral opening to receive the suture. An actuator coupled to the needle enables the user to move the needle proximally to align the notch with the lateral slot.

Abstract: A suture anchor is described which in one form may be easily fabricated from extruded material by angular cuts and bore holes which provide an offset pulling force to the suture. In an alternate and preferred embodiment the suture anchor is injection molded having an annular displaced corner and abutment wall which act to seat the suture anchor firmly within a bore hole. Novel application means are also disclosed which hold the suture anchor on a frangible shaft for insertion and upon completion of the insertion permit fracture of the frangible portion and removal of the instrument.

Abstract: A method and apparatus for fixing a ligament in a bone tunnel by cross-pinning the ligament in the bone tunnel.

Abstract: A device for snaring cord-like objects is provided. The device comprises a hollow shaft having a pointed distal end, a rod having a pair of wires attached to its distal end, the wires being spring biased away from one another, and activation means. The rod and wires are located in the lumen of the shaft in reciprocally movable relationship therewith. The activation means is attached to the proximal ends of the shaft and the rod so as to allow the controlled movement of the rod and wires relative to the shaft. One of the wire-like elements defines a hook-shaped configuration at its distal end. The device allows the wire-like elements to be selectively located within the distal end of the shaft or in a configuration wherein the wire-like elements extend outwardly from the distal end of the shaft in flaring relationship to one another.

Abstract: A suture anchor is provided having a body with at least one suture-receiving channel that extends distally from a proximal end of the body. The suture-receiving channel can include a cavity formed in a distal-most end of the body, or it can terminate at a transversely-extending bore formed through the body. The suture anchor can also include a suture loop that is positioned within the suture-receiving channel and cavity or bore, and that includes a proximal portion that extends proximal of the proximal end of the body.

Abstract: A suture anchor is described which in one form may be easily fabricated from extruded material by angular cuts and bore holes which provide an offset pulling force to the suture. In an alternate and preferred embodiment the suture anchor is injection molded having an annular displaced corner and abutment wall which act to seat the suture anchor firmly within a bore hole. Novel application means are also disclosed which hold the suture anchor on a frangible shaft for insertion and upon completion of the insertion permit fracture of the frangible portion and removal of the instrument.

Abstract: A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.

Abstract: Methods and compositions for producing therapeutic agents using chondrocytes are provided. The genetically engineered chondrocytes can be used to express the therapeutic agent in a subject, including in an environment typically associated with chondrocytes and in an environment not typically associated with chondrocytes.

Abstract: A fluid jet cutting system that provides more consistent cutting jet performance is disclosed. The system includes a fluid pump for pressurizing fluid having a fluid inlet and a fluid outlet. The pump delivers pressurized fluid to a delivery tube that is in fluid communication with an end effector. The end effector includes an orifice for delivering pressurized fluid to tissue. The power delivered to the pump is controlled to produce a desired fluid cutting jet.

Abstract: A resorbable interbody fusion device for use in spinal fixation is disclosed. The device is composed of 25–100% bioresorbable or resorbable material. The interbody fusion device of the invention can be in any convenient form, such as a wedge, screw or cage. Preferably, the resorbable device of the invention is in the shape of a tapered wedge or cone, which further desirably incorporates structural features such as serrations or threads better to anchor the device in the adjoining vertebrae. The preferred device further comprises a plurality of peripheral voids and more desirably a central void space therein, which may desirably be filled with a grafting material for facilitating bony development and/or spinal fusion, such as an autologous grafting material.

Abstract: A rivet-like bone anchor has a floating washer at its head that can adapt to an angled bone surface and, thereby, better secure a tissue thereto. The anchor includes a rivet, an expandable sleeve, and a washer. The rivet includes a head and an elongate body having proximal and distal ends, the head being mounted on the proximal end of the elongate body. The expandable sleeve has an inner bore adapted to receive the rivet body. The washer “floats” at a proximal end of the sleeve. As the rivet is inserted into sleeve, the sleeve expands into an interference fit with the bone. The head of the rivet, moreover, forces the floating washer into contact with the tissue at an angle that conforms to that of the underlying bone surface. A deployment tool permits the anchor to be deployed without application of unnecessary counterforce. The tool includes an outer tube, the distal end of which can hold the anchor housing, e.g., via a screw fit.

Abstract: Various methods and devices are provided for cutting and sculpting body tissue, such as cartilage and the like, during a surgical procedure. In an exemplary embodiment, a surgical cutting device is provided which includes an elongate shaft and a rotatable tissue-affecting tip disposed at the distal end thereof. A lumen extends through both the shaft and the tip, and terminates in an opening formed in a distal end of the tissue-affecting tip.

Abstract: A high pressure fluid jet system is provided, which is useful for cutting hard material during a surgical procedure. The cutting of hard material is more efficient as the system delivers abrasive solid particles with the high pressure fluid. In an exemplary embodiment, abrasive solid particles can be mixed with a pressurized stream of fluid prior to delivery of the fluid to a nozzle of an application tool. Alternatively, the abrasive solid particles can be entrained in the pressurized fluid stream or the pressurized fluid stream can erode a solid or suspension form of the abrasive particles.

Abstract: Various surgical fluid jet cutting instruments for selective bulk removal and precision sculpting of tissue are provided. In one exemplary embodiment, the instrument can include a fluid delivery tube having a nozzle for forming a high pressure fluid jet, and at least two evacuation tubes that are adapted to be selectively and removably coupled to the fluid delivery tube. Each evacuation tube can have an evacuation port or jet-receiving opening that is adapted to be positioned opposite to and spaced apart from the nozzle for receiving the high pressure fluid jet. Each evacuation tube can also be adapted for a specific use. For example, the instrument can include a first evacuation tube that is adapted to allow bulk removal of tissue, and a second evacuation tube that is adapted to allow precision sculpting of tissue.