Abstract: The present invention is directed to bioactive compositions that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in vivo. More particularly the present invention is directed to the use of compositions comprising an effective amount of bone sialoprotein to enhance the repair of damaged or diseased bone.
Type:
Grant
Filed:
September 17, 1999
Date of Patent:
October 1, 2002
Assignee:
DePuy Orthopeadics
Inventors:
Dale R. Peterson, Nancy Nousek-Goebl, Todd P. Glancy