Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.
Type:
Grant
Filed:
July 20, 2017
Date of Patent:
October 18, 2022
Assignees:
MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG, DER WISSENSCHAFT EN E.V., TECHNISCHE UNIVERSITÄT MÜNCHEN
Inventors:
Anahita Javaheri, Tobias Kruse, Markus Gerhard, Bernhard B. Singer, Daniel Hornburg, Han Remaut, Matthias Mann, Felix Meissner, Steffen Backert