Abstract: The present invention relates to a health monitoring system comprising an implantable sensor configured to measure impedance within a body tissue of the subject resulting from an electrical current flowing through said body tissue, wherein the body tissue is sub-dermal or subcutaneous tissue of said subject, the sensor including a powering and communication circuit having a coil configured to be powered by an electromagnetic field and to communicate with external devices.

Abstract: The present invention relates to an implantable sensor configured to be implanted within the body of the subject and being configured to measure impedance within a body tissue of the subject resulting from an electrical current flowing through the body tissue, wherein the body tissue is sub-dermal or subcutaneous tissue of the subject. One pair of injection electrodes is configured for injection of electrical current into the body tissue and one pair of sensing electrodes is configured to detect the resulting voltage. A detector is operatively connected to the sensing electrodes and is configured to receive the voltage detected by the sensing electrodes, wherein the detector is configured to measure the impedance of the body tissue based on the voltage detected by the pair of sensing electrodes.

Abstract: A method for producing local analgesia in a subject having a site of local discomfort comprises administration of an aliphatic polyamine and, preferably, urea. A composition of the invention comprises an aliphatic polyamine and preferably urea. The polyamine can be an alkylamine, such as, preferably, putrescine. The composition can also include lidocaine and/or a copper containing component.

Abstract: A method and apparatus is disclosed for non-invasively determining glucose levels in a fluid of a subject, typically the blood glucose level. The impedance of skin tissue is measured and the measurement is used with impedance measurements previously correlated with directly determined glucose levels to determine the glucose level from the newly measured impedance. It is thus possible, to routinely non-invasively determine fluid glucose levels.

Abstract: Method for non-invasively determining glucose level in fluid of subject, typically blood glucose level. A particular device is mounted on the skin of the patient for a fixed period of time. The device is mounted on the skin such that a substrate such as paper or gel or an aqueous glucose solution carried by the device are in contact with the patient's skin. Water and/or glucose migrates between the substrate or the aqueous glucose solution of the device. The degree of migration of the substance in question is monitored, for example the amount of glucose remaining in an aqueous solution of the device is measured at the end of the fixed period. This can be done by a conventional or other spectrophotometric method, for example. The glucose level is determined based on the degree of migration of the migrating substance. That is, the degree of migration is correlated with previously determined fluid glucose levels based on directly measured fluid glucose levels.

Abstract: The present invention comprises a topical analgesic composition comprising an analgesic agent, an alcohol, a chaotropic agent and an unsaturated fatty acid. The composition is preferably in the form of a stable gel and may further comprise a pharmaceutically acceptable emulsifier, a pharmaceutically acceptable gelling and/or thickening agent, and a pharmaceutically acceptable preservative. The pH of the composition is adjusted to 7.5-8.0 by the addition of a pharmaceutically acceptable organic base, such as triethanolamine.The invention also comprises a method for inducing topical analgesia. The composition is absorbed on an absorbent material, for example a cotton strip inserted into typical skin-wipe packet; brought in contact with the skin of a person in need of such an analgesia; and maintained in contact with the skin for a period of time sufficient to induce and maintain topical analgesia.