Abstract: Among other things, disclosed herein are compositions and methods for using human-isolated or synthetic Alcaligenes faecalis, Bacillus altitudinis, Bacillus pumilus, Bacillus subtilis, or Janthinobacterium lividum. Compositions may improve skin health. Methods may include applying human-isolated or synthetic Alcaligenes faecalis, Bacillus altitudinis, Bacillus pumilus, Bacillus subtilis, or Janthinobacterium lividum over a host or host area, such as skin or mucosa to minimize the presence of one or more pathogenic microbes, maximize therapeutic effects of one or more additional therapeutics, and/or improve health of a host or host area.
Type:
Grant
Filed:
October 13, 2021
Date of Patent:
August 18, 2026
Assignee:
DermBiont, Inc.
Inventors:
Robert Brucker, Yanjun Huang, Nikola Jovanovic, Bhanu Prakash Chowdary Sakhamuri, Ida Lister, Xuecheng Zhang, Sanjay Jain, Emma Jean Mildred Taylor
Abstract: Provided herein are compositions comprising ruboxistaurin free base and its salts thereof and methods of use for treating conditions of the skin.
Abstract: Disclosed herein are compositions and methods for using human-derived Janthinobacterium lividum. Compositions improve skin health. Methods may include applying human-derived Janthinobacterium lividum over a host or host area, such as skin or mucosa, to minimize the presence of one or more microbes, maximize therapeutic effects, and/or improve health. A method to minimize a pathogenic microbe may include applying to a surface a composition including human-derived Janthinobacterium lividum and an acceptable carrier. Compositions and methods may include a prebiotic to maximize growth and/or metabolites. Compositions and methods may include human-derived Janthinobacterium lividum metabolites, such as violacein, prodigiosin, indole-3-carboxaldehyde, and lantibiotics, and/or other Postbiotics.
Type:
Grant
Filed:
April 28, 2021
Date of Patent:
August 20, 2024
Assignee:
DermBiont, Inc.
Inventors:
Robert M. Brucker, Xuecheng Zhang, Ida Lister, Sanjay Jain
Abstract: Disclosed herein are compositions and methods for using human-derived Janthinobacterium lividum. Compositions improve skin health. Methods may include applying human-derived Janthinobacterium lividum over a host or host area, such as skin or mucosa, to minimize the presence of one or more microbes, maximize therapeutic effects, and/or improve health. A method to minimize a pathogenic microbe may include applying to a surface a composition including human-derived Janthinobacterium lividum and an acceptable carrier. Compositions and methods may include a prebiotic to maximize growth and/or metabolites. Compositions and methods may include human-derived Janthinobacterium lividum metabolites, such as violacein, prodigiosin, indole-3-carboxaldehyde, and lantibiotics, and/or other Postbiotics.
Type:
Grant
Filed:
May 27, 2020
Date of Patent:
June 22, 2021
Assignee:
DermBiont, Inc.
Inventors:
Robert M. Brucker, Xuecheng Zhang, Ida Lister, Sanjay Jain