Abstract: The present invention provides compositions and methods for use in the treatment of hyperproliferative dermal diseases. Specifically, the present invention teaches pharmaceutical compositions for topical administration consisting essentially of a vitamin D metabolite, calcipotriol, and nicotinamide, which are particularly effective in treating and in the maintenance therapy of psoriasis and other related dermal disorders and diseases.
Type:
Grant
Filed:
September 30, 2015
Date of Patent:
March 28, 2017
Assignee:
Dermipsor Ltd.
Inventors:
Avikam Harel, Zeev Even-Chen, Olga Bloch
Abstract: The present invention provides compositions and methods for use in the treatment of hyperproliferative dermal diseases. Specifically, the present invention teaches pharmaceutical compositions for topical administration where the compositions contain nicotinamide and a vitamin D metabolite, calcipotriol, which are particularly effective in treating and in the maintenance treatment of psoriasis and other related dermal disorders and diseases.
Type:
Grant
Filed:
May 10, 2006
Date of Patent:
November 3, 2015
Assignee:
Dermipsor Ltd.
Inventors:
Avikam Harel, Zeev Even-Chen, Olga Bloch
Abstract: Compositions useful for the treatment of hyperproliferative dermal diseases of the scalp. Specifically, topical gel and liquid compositions that include calcipotriol and nicotinamide in a polyethylene glycol-based carrier, for topical application to the scalp.
Abstract: Compositions useful in the treatment of skin atrophy and improvement of skin appearance and texture are disclosed. The methods include the topical administration of vitamin D3 or specific vitamin D3 analogs as an essential ingredient either on its own or in combination with cADPR and or nicotinamide. The compositions are particularly effective in preventing and treating signs of chronological and or photoaging including fine lines, wrinkles and discoloration.
Type:
Grant
Filed:
May 10, 2006
Date of Patent:
October 11, 2011
Assignee:
Dermipsor Ltd.
Inventors:
Avikam Harel, Zeev Even-Chen, Olga Bloch
Abstract: The present invention provides compositions and methods for use in the treatment of hyperproliferative dermal diseases. Specifically, the present invention teaches pharmaceutical compositions for topical administration where the compositions contain nicotinamide and a vitamin D metabolite, calcipotriol, which are particularly effective in treating and in the maintenance treatment of psoriasis and other related dermal disorders and diseases.
Type:
Application
Filed:
May 10, 2006
Publication date:
May 21, 2009
Applicant:
Dermipsor Ltd.
Inventors:
Avikam Harel, Zeev Even-Chen, Bloch Olga