Abstract: Disclosed is a syringe assembly which greatly reduces the chances of an operator coming in contact with an infectious needle. The syringe assembly is initially provided with its needle retracted within its barrel, in a sterile and safe environment. When used, the needle is engaged by the plunger, and locked in place at the forward end of the syringe barrel. Before disposal, the needle is withdrawn back into the barrel, and the plunger is broken off. Thus, the disposed of syringe is incapable of being reused, and there is little or no danger of accidental punctures, because the needle is retained within the syringe barrel.