Abstract: A wheel well fairing for reducing drag on an aircraft fuselage configured with an open wheel well for stowing landing gear of the aircraft. The wheel well fairing includes a Coanda fairing having a convex-shaped lower portion and an upper portion. The upper portion is configured for positioning adjacent an interior vertically-orientated sidewall of the wheel well, and the convex-shaped lower portion has a bottom surface configured to extend substantially parallel to and positioned adjacent with an outer hull surface of the fuselage. The convex-shaped lower portion is curved inwardly within the wheel well between the upper portion and bottom surface. The Coanda fairing is positioned at an aft portion of the wheel well to redirect airflow out of the wheel well in a rearward direction along the bottom hull surface of the fuselage.

Abstract: The present invention relates to methods and compositions for reducing the immunogenicity of chimeric Notch receptors, and specifically to transcription factors useful for controlling gene expression delivered to tissues by such chimeric Notch receptors.

Abstract: Methods and compositions are provided for reversibly localizing proteins to the exterior part of the cell surface. Compositions provided herein can include nucleic acids that encode polypeptides of interest and the ligand binding domain (LBD) of a nuclear hormone receptor. Medical applications are provided, including controlling the toxicity of CAR T cells.

Abstract: In accordance with the principals of the present invention, a desk or executive curio is provided. A rotor assembly includes a rotor and a shaft. A housing assembly defines inner pivoted supports that allow rotation of the rotor about an inner pivotal axis. The housing assembly further defines outer pivoted supports that allow rotation of the housing about an outer pivotal axis perpendicular to the inner pivotal axis of the rotor assembly. Bearings allow the rotor assembly and the housing assembly to be held in an axis perpendicular to a rotor axis. The rotor assembly and the housing assembly are removably connectable to a base along the inner pivotal axis, the base having an offset center of gravity and defining a curved outer surface.

Abstract: A carrier apparatus is disclosed for attachment to a bicycle to carry a number of items including sporting good items. In one embodiment, the apparatus includes a receptacle suspended from a fixed rear support and a movable front support. The receptacle includes a panel having a rear end connected to the rear support and a front end connected to the front support to cause the receptacle to be suspended therefrom. The apparatus includes a resilient member connecting the front support to the rear support, wherein the front support is tetheringly movable toward and away from the rear support to vary the opening and closing of the receptacle to receive and thereafter secure therein a plurality of differently sized items.

Abstract: A carrier apparatus is disclosed for attachment to a bicycle to carry a number of items including sporting good items. In one embodiment, the apparatus includes a receptacle suspended from a fixed rear support and a movable front support. The receptacle includes a panel having a rear end connected to the rear support and a front end connected to the front support to cause the receptacle to be suspended therefrom. The apparatus includes a resilient member connecting the front support to the rear support, wherein the front support is tetheringly movable toward and away from the rear support to vary the opening and closing of the receptacle to receive and thereafter secure therein a plurality of differently sized items.

Abstract: A sleeve that is removably attachable to an animal feeding bowl is shown and described. The sleeve is elastomeric and is stretched radially when in attached condition to fit snugly to the animal feeding bowl. The sleeve includes a flange at one end that projects radially inward to create an anti-skid surface that prevents the bowl from skidding along floors, counter tops, and other surfaces on which the bowl is placed.

Abstract: A lawn bag apparatus to stabilize an opening of a lawn bag is disclosed, comprising a frame comprising a plurality of sidewalls arranged to approximate the opening, each sidewall comprising a midwall portion extending approximately vertically, an upper wall portion extending upwardly and outwardly from the midwall portion, and a lower wall portion extending downwardly and inwardly from the midwall portion, a first clamp positioned along one of the sidewalls, and a second clamp positioned along a sidewall opposite the first clamp, the first and second clamps being movable between an open, disengaged position and a closed, engaged position for detachably securing the frame to the lawn bag.

Abstract: A lawn bag apparatus to stabilize an opening of a lawn bag is disclosed, comprising a frame comprising a plurality of sidewalls arranged to approximate the opening, each sidewall comprising a midwall portion extending approximately vertically, an upper wall portion extending upwardly and outwardly from the midwall portion, and a lower wall portion extending downwardly and inwardly from the midwall portion, a first clamp positioned along one of the sidewalls, and a second clamp positioned along a sidewall opposite the first clamp, the first and second clamps being movable between an open, disengaged position and a closed, engaged position for detachably securing the frame to the lawn bag.

Abstract: The invention includes improvements to a security holster including protective ridges for use around the release mechanism and the locking mechanism. Also included is a mortise and tenon arrangement for securing the holster body to a belt attachment plate.

Abstract: An ergonomic duty belt having a pliable outer covering, a semi-rigid frame member configured to form a semi-conically shaped section when placed about the waist of a user and to conform to the shape of a user's body. This semi conical shape provides for increased ergonomic comfort and decreased pain and discomfort to the wearer of the belt. This duty belt also has an accessory attachment system comprised of generally horizontally extending track portions as well as generally vertically oriented vertical plates. A variety of attachments having attachment portions configured to attach to the track sections and to these vertically oriented plates as well as to a traditional duty belt connect accessories to the duty belt.

Abstract: A security holster for handguns which utilizes a U-shaped rod as part of the locking and releasing mechanism. The user presses a handgun against a portion of the U-shaped rod, which pushed the U-shaped rod forward, and causes the locking tab to seat against the ejection port or another feature of the handgun.

Abstract: The invention is a security holster configured for use by left-handed users, with a release tab on the left side of the holster, a locking tab on the right side of the holster, which generally engages the ejection port of a gun, and a linkage between the release tab and the locking tab.

Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.