Abstract: The present invention relates to the use of staphylokinase for the preparation of a pharmaceutical composition for treating arterial thrombosis, such as e.g. myocardial infarction. It is demonstrated that staphylokinase can be particularly useful as a thrombolytic agent for the lysis of platelet-rich clots. Furthermore it is demonstrated that staphylokinase, unlike streptokinase, does not induce antibody induction upon repeated administration.
Type:
Grant
Filed:
July 14, 1993
Date of Patent:
August 9, 1994
Assignees:
Leuven Research & Development vcw, Desire J. Collen
Inventors:
Desire J. Collen, Jean-Marie Stassen, Henri R. Lijnen