Patents Assigned to Detlev Ganten
  • Transgenic rats containing at least one human gene which participates in blood pressure control
    Patent number: 5731489
    Abstract: The present invention relates to transgenic rats in the genome of which at least one human gene is integrated the gene product of which participates in blood pressure control. More specifically, the invention relates to transgenic rats and their offspring exhibiting increased blood pressure (>90/>140 mm Hg) or high blood pressure (>95/>160 mm Hg). Finally, the invention relates to processes for the production of the transgenic rats of the present invention and their offspring and their use for pharmacological tests.
    Type: Grant
    Filed: January 17, 1995
    Date of Patent: March 24, 1998
    Assignee: Detlev Ganten
    Inventors: Detlev Ganten, John Mullins, Kazuo Murakami