Patents Assigned to Deutsches Institut für Ernährungsforschung
  • Methods for isolating ligands of the human bitter taste receptor TAS2R49
    Patent number: 8709745
    Abstract: The present invention relates to agonists and antagonists of the human bitter-taste receptor hTAS2R49. The invention also relates to methods for identifying further molecules that suppress or enhance hTAS2R49-mediated bitter taste transduction or bitter taste response and uses thereof.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: April 29, 2014
    Assignee: Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
    Inventors: Claudia Batram, Wolfgang Meyerhof
  • Bitter taste receptors
    Patent number: 8709737
    Abstract: The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block, bitter taste transduction, or enhance bitter taste response.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: April 29, 2014
    Assignee: Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand
    Inventors: Bernd Bufe, Thomas Hofmann, Dietmar Krautwurst, Christina Kuhn, Wolfgang Meyerhof
  • Agonists of bitter taste receptors and uses thereof
    Patent number: 8524465
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R14, hTAS2R10 and hTAS2R4 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R14, hTAS2R10 and hTAS2R4 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: September 3, 2013
    Assignee: Deutsches Institut fuer Ernaehrungsforschung Potsdam-Rehbruecke
    Inventors: Maik Behrens, Anne Brockhoff, Christina Kuhn, Wolfgang Meyerhof, Giovanni Appendino
  • AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF
    Publication number: 20120309703
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R14, hTAS2R10 and hTAS2R4 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R14, hTAS2R10 and hTAS2R4 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: August 13, 2012
    Publication date: December 6, 2012
    Applicant: Deutsches Institut Fuer Ernaehrungsforschung Potsdam-Rehbruecke
    Inventors: Maik BEHRENS, Anne Brockhoff, Christina Kuhn, Wolfgang Meyerhof, Giovanni Appendino
  • Agonists of bitter taste receptors and uses thereof
    Patent number: 8309314
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R14, hTAS2R10 and hTAS2R4 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R14, hTAS2R10 and hTAS2R4 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: November 13, 2012
    Assignee: Deutsches Institut Fuer Ernaehrungsforschung Potsdam-Rehbruecke
    Inventors: Maik Behrens, Anne Brockhoff, Christina Kuhn, Wolfgang Meyerhof, Giovanni Appendino
  • Antagonists of bitter taste receptors and uses thereof
    Patent number: 8158442
    Abstract: The present invention relates to antagonists of the human bitter-taste receptors hTAS2R38. The invention also relates to methods for identifying further molecules that suppress hTAS2R38 mediated bitter taste transduction or bitter taste response and uses thereof.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: April 17, 2012
    Assignee: Deutsches Institut Fuer Ernaehrungsforschung Potsdam-Rehbruecke-Stiftung Des Oefentlichen Rechts
    Inventors: Bernd Bufe, Christina Kuhn, Wolfgang Meyerhof
  • Agonists of a bitter taste receptor and uses thereof
    Patent number: 8158372
    Abstract: The present invention relates to agonists of the hTAS2R14 bitter taste receptor and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R14 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: April 17, 2012
    Assignee: Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
    Inventors: Maik Behrens, Anne Brockhoff, Bernd Bufe, Christina Kuhn, Wolfgang Meyerhof, Marcel Winnig
  • Methods of identifying agonists and antagonists of hTASR bitter taste receptors
    Patent number: 8043823
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R46, hTAS2R47 and hTAS2R50 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R46, hTAS2R47 and hTAS2R50 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 25, 2011
    Assignee: Deutsches Institut fuer Ernaehrungsforschung
    Inventors: Maik Behrens, Anne Brockhoff, Christina Kuhn, Wolfgang Meyerhof, Giovanni Appendino, Valeria D'Auria
  • PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE
    Publication number: 20110045069
    Abstract: A description is given of precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease, in particular for the prevention or treatment of Type 2 diabetes. A description is also given of uses of these precursor compounds and edible compositions, preparations for nutrition or pleasure or semi-finished products and pharmaceutical preparations, containing such precursor compounds.
    Type: Application
    Filed: July 15, 2010
    Publication date: February 24, 2011
    Applicants: SYMRISE Gmbh Co. KG, Deutsches Institut für Ernährungsforschung
    Inventors: Jakob Peter Ley, Michael Backes, Tobias Vössing, Frauke Stähler, Wolfgang Meyerhof, Christian Wintermeyer
  • AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF
    Publication number: 20100184796
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R46, hTAS2R47 and hTAS2R50 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R46, hTAS2R47 and hTAS2R50 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: March 31, 2008
    Publication date: July 22, 2010
    Applicant: DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE
    Inventors: Maik Behrens, Anne Brockhoff, Wolfgang Meyerhof, Giovanni Appendino, Valeria D' Auria
  • Method for the identification of antagonists of a phenylthiocarbamide/bitter taste receptor
    Patent number: 7413867
    Abstract: The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block bitter taste transduction, or enhance bitter taste response.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: August 19, 2008
    Assignee: Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand
    Inventors: Bernd Bufe, Thomas Hofmann, Dietmar Krautwurst, Christina Kuhn, Wolfgang Meyerhof