Patents Assigned to DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM-REHBRUCKE
  • Methods for isolating ligands of the human bitter taste receptor TAS2R49
    Patent number: 8709745
    Abstract: The present invention relates to agonists and antagonists of the human bitter-taste receptor hTAS2R49. The invention also relates to methods for identifying further molecules that suppress or enhance hTAS2R49-mediated bitter taste transduction or bitter taste response and uses thereof.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: April 29, 2014
    Assignee: Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
    Inventors: Claudia Batram, Wolfgang Meyerhof
  • Methods of identifying antagonists of the hTAS2R46 bitter taste receptor
    Patent number: 8673578
    Abstract: The present invention relates to antagonists and agonists of the human bitter-taste receptors hTAS2R40, hTAS2R43, hTAS2R44, hTAS2R46, and hTAS2R47. The invention also relates to methods for identifying further molecules that suppress or enhance bitter taste transduction or bitter taste response mediated by hTAS2R40, hTAS2R43, hTAS2R44, hTAS2R46, and/or hTAS2R47 and uses thereof.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: March 18, 2014
    Assignee: Deutsches Institut für Ernahrungsforschung Potsdam-Rehbrücke
    Inventors: Giovanni Appendino, Maik Behrens, Anne Brockhoff, Wolfgang Meyerhof
  • Agonists of bitter taste receptors and uses thereof
    Patent number: 8168403
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R40 and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R40 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: May 1, 2012
    Assignee: Deutsches Institut fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung Des Offentlichen Rechts
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • Agonists of a bitter taste receptor and uses thereof
    Patent number: 8158372
    Abstract: The present invention relates to agonists of the hTAS2R14 bitter taste receptor and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R14 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: April 17, 2012
    Assignee: Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
    Inventors: Maik Behrens, Anne Brockhoff, Bernd Bufe, Christina Kuhn, Wolfgang Meyerhof, Marcel Winnig
  • Agonists of bitter taste receptors and uses thereof
    Patent number: 8012701
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R3 and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R3 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: September 6, 2011
    Assignee: Deutsches Institut fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • Agonists of bitter taste receptors and uses thereof
    Patent number: 7998692
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R7 and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R7 bitter taste transduction or bitter taste response.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: August 16, 2011
    Assignee: Deutsches Institut fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • Agonists of Bitter Taste Receptors and Uses Thereof
    Publication number: 20110077308
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R40 and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R40 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: September 27, 2010
    Publication date: March 31, 2011
    Applicant: DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM-REHBRUCKE STIFTUNG DES OFFENTLICHEN RECHTS
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • Agonists of Bitter Taste Receptors and Uses Thereof
    Publication number: 20110039757
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R3 and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R3 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: September 27, 2010
    Publication date: February 17, 2011
    Applicant: DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM-REHBRUCKE STIFTUNG DES OFFENTLICHEN RECHTS
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • Agonists of Bitter Taste Receptors and Uses Thereof
    Publication number: 20110034369
    Abstract: The present invention relates to agonists of the human bitter-taste receptor hTAS2R7 and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R7 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: September 27, 2010
    Publication date: February 10, 2011
    Applicant: DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM-REHBRUCKE
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn
  • AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF
    Publication number: 20100184796
    Abstract: The present invention relates to agonists of the human bitter-taste receptors hTAS2R46, hTAS2R47 and hTAS2R50 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R46, hTAS2R47 and hTAS2R50 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: March 31, 2008
    Publication date: July 22, 2010
    Applicant: DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE
    Inventors: Maik Behrens, Anne Brockhoff, Wolfgang Meyerhof, Giovanni Appendino, Valeria D' Auria
  • ANTAGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF
    Publication number: 20100113548
    Abstract: The present invention relates to antagonists of the human bitter-taste receptors hTAS2R38. The invention also relates to methods for identifying further molecules that suppress hTAS2R38 mediated bitter taste transduction or bitter taste response and uses thereof.
    Type: Application
    Filed: April 18, 2008
    Publication date: May 6, 2010
    Applicant: DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM-REHBRUCKE
    Inventors: Bernd Bufe, Christina Kuhn, Wolfgang Meyerhof
  • Agonists of Bitter Taste Receptors and Uses Thereof
    Publication number: 20080213761
    Abstract: The present invention relates to agonists of the hTAS2R1, hTAS2R3, hTAS2R7 and hTAS2R40 bitter taste receptors, respectively, and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R1, hTAS2R3, hTAS2R7 or hTAS2R40 bitter taste transduction or bitter taste response.
    Type: Application
    Filed: November 18, 2005
    Publication date: September 4, 2008
    Applicant: Deutsches Institut Fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung Des Offentlichen Rechts
    Inventors: Bernd Bufe, Wolfgang Meyerhof, Christina Kuhn