Patents Assigned to DEUTSCHES KREBSFORSCHUNGCZENTRUM
  • Use Of The Foamy Virus Bet Protein For Inactivating APOBEC
    Publication number: 20090202488
    Abstract: Described is the foamy virus Bet-mediated inactivation of the mutagenic, genome-modifying and vector-inactivating cellular enzyme ABOBEC. Such inactivation is useful for the treatment or prevention of various diseases, e.g., cancer, or for enhancing the production and genetic stability of gene therapy vectors, preferably retroviral vectors.
    Type: Application
    Filed: June 6, 2005
    Publication date: August 13, 2009
    Applicant: DEUTSCHES KREBSFORSCHUNGCZENTRUM
    Inventors: Martin Löchelt, Carsten Münk