Abstract: The present invention relates to nucleoside derivatives having photolabile protective groups of general formula (I)
in which
R1=H, NO2, CN, OCH3, halogen, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms,
R2=H, NO2, CN, OCH3, halogen, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms,
R3=H, halogen, NO2, CN, OCH3, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or aliphatic acyl residue having 2 to 5 C atoms,
R4=H, halogen, NO2, CN, OCH3, an alkyl, alkoxy, or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or aliphatic acyl residue having 2 to 5 atoms,
R5=H, dimethoxytrityl or a protective group common in the chemistry of nucleotides or a functional group com
Type:
Grant
Filed:
February 21, 2002
Date of Patent:
June 29, 2004
Assignee:
Deutsches Krebsforschungszentrum Stiftund des Offentlichen
Rechts
Abstract: This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.
Type:
Grant
Filed:
October 14, 1997
Date of Patent:
November 21, 2000
Assignee:
Deutsches Krebsforschungszentrum Stiftund des Offentlichen Rechts
Inventors:
Hannsjorg Sinn, Hans-Hermann Schrenk, Wolfgang Maier-Borst, Gerd Stehle