Patents Assigned to DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
  • Inhibitors of thioredoxin-interacting protein (TXNIP) for therapy
    Publication number: 20150152169
    Abstract: Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (TXNIP) or (b) the expression of the gene encoding TXNIP for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.
    Type: Application
    Filed: April 17, 2013
    Publication date: June 4, 2015
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
    Inventors: Peter Krammer, Karsten Gülow, Sabine Sass
  • MODULATORS OF ADP-DEPENDENT GLUCOKINASE (ADPGK) AND GLYCEROL-3-PHOSPHATE DEHYDROGENASE (GPD2) FOR THERAPY
    Publication number: 20140171624
    Abstract: Described are compounds capable of modulating (a) the biological activity of ADP-dependent glucokinase (ADPGK) and/or glycerol-3-phosphate dehydrogenase (GPD2) or (b) the expression of the gene encoding ADPGK or GPD2 for use in treating a disease (a) associated with aberrant cell proliferation, e.g., a neoplasm, or (b) of the immune system, e.g., an autoimmune disease.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 19, 2014
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
    Inventors: Peter Krammer, Marcin M. Kaminski, Karsten Gulow, Sven W. Sauer