Patents Assigned to Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechtes
  • REARRANGED TT VIRUS MOLECULES FOR USE IN DIAGNOSIS, PREVENTION AND TREATMENT OF CANCER AND AUTOIMMUNITY
    Publication number: 20170066802
    Abstract: The present invention relates to rearranged molecules of (a) a specific TT virus sequence and (b) a nucleotide sequence encoding a polypeptide showing homology to mammalian proteins associated with cancer and autoimmune diseases that are capable of replicating autonomously for use in diagnosis, prevention and treatment of diseases like cancer and autoimmunity.
    Type: Application
    Filed: December 19, 2012
    Publication date: March 9, 2017
    Applicant: Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechtes
    Inventors: Ethel-Michele De Villiers, Harald Zur Hausen
  • Inhibitors of thioredoxin-interacting protein (TXNIP) for therapy
    Publication number: 20150152169
    Abstract: Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (TXNIP) or (b) the expression of the gene encoding TXNIP for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.
    Type: Application
    Filed: April 17, 2013
    Publication date: June 4, 2015
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
    Inventors: Peter Krammer, Karsten Gülow, Sabine Sass
  • MODULATORS OF ADP-DEPENDENT GLUCOKINASE (ADPGK) AND GLYCEROL-3-PHOSPHATE DEHYDROGENASE (GPD2) FOR THERAPY
    Publication number: 20140171624
    Abstract: Described are compounds capable of modulating (a) the biological activity of ADP-dependent glucokinase (ADPGK) and/or glycerol-3-phosphate dehydrogenase (GPD2) or (b) the expression of the gene encoding ADPGK or GPD2 for use in treating a disease (a) associated with aberrant cell proliferation, e.g., a neoplasm, or (b) of the immune system, e.g., an autoimmune disease.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 19, 2014
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
    Inventors: Peter Krammer, Marcin M. Kaminski, Karsten Gulow, Sven W. Sauer
  • REARRANGED TT VIRUS MOLECULES FOR USE IN DIAGNOSIS, PREVENTION AND TREATMENT OF CANCER AND AUTOIMMUNITY
    Publication number: 20130259869
    Abstract: The present invention relates to rearranged molecules of (a) a specific TT virus sequence and (b) a nucleotide sequence encoding a polypeptide showing homology to mammalian proteins associated with cancer and autoimmune diseases that are capable of replicating autonomously for use in diagnosis, prevention and treatment of diseases like cancer and autoimmunity.
    Type: Application
    Filed: December 19, 2012
    Publication date: October 3, 2013
    Applicant: Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechtes
    Inventor: Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechtes