Abstract: Combined treatment for cancer is provided. Accordingly, there is provided a method of selecting or determining therapeutic efficacy of a combination of agents for the treatment of cancer in a subject in need thereof, the method comprising: (i) culturing a cancerous tissue of the subject in an ex-vivo organ culture (EVOC) in the presence of a combination of an anti-cancer agent and an additional agent, said additional agent is inhibiting expression and/or activity of a target conferring innate resistance to said anti-cancer agent or increasing expression and/or activity of a target conferring innate sensitivity to said anti-cancer agent; and (ii) determining an anti-cancer effect of the combination on the tissue, wherein responsiveness of the tissue to the combination indicates the combination is efficacious for the treatment of the cancer in the subject.

Abstract: A unified learning approach for large-scale ride-hailing is described, the approach includes obtaining an offline state value network for predicting a value of a vehicle state, the offline state value network being trained based on a plurality of historical vehicle trajectories; initializing an online state value network and dispatching a plurality of vehicles according to the online state value network for a period of time; training the online state value network based on vehicle states of the plurality of vehicles before and after the dispatching and rewards associated with the dispatching; ensembling the trained online state value network and the offline state value network to obtain an ensembled online state value network; and dispatching the plurality of vehicles according to the ensembled online state value network.

Abstract: An atomization generator and a special high-pressure atomization generation device for increasing oil and gas field recovery are provided. The special high-pressure atomization generation device for increasing oil and gas field recovery includes an agent pot assembly, a gear pump, a metering pump, an atomization generator and pipelines. The gear pump is connected with the agent pot assembly through an agent pot liquid inlet pipe. The metering pump is arranged between the agent pot assembly and the atomization generator which are connected through the low-pressure manifold pipeline and the high-pressure liquid inlet pipeline. The high-pressure liquid inlet pipeline is connected with the liquid inlet pipe. The liquid inlet pipes are connected with the metering pump. The gas inlet pipe is connected with the high-pressure gas source through the high-pressure gas inlet pipe. The gas inlet cap is provided with a gas inlet pipe.

Abstract: Methods and kits for diagnosing or monitoring systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to a specific antibody reactivity profile useful in diagnosing or monitoring SLE in a subject.

Abstract: The present disclosure a temperature-resistant and salt-resistant modified nano-graphite dispersed particle gel system with a strong self-growth effect.

Abstract: Methods of generating a synthetic embryo are provided. Accordingly, there is provided a method of generating a synthetic embryo comprising inducing expression of a factor that induces differentiation to trophectoderm cells in a subpopulation of naïve pluripotent stem cells (PSCs) to obtain a trophectoderm primed cells; inducing expression of a factor that induces differentiation to extra embryonic primitive endodermal cells in a second subpopulation of naïve PSCs to obtain extra embryonic primitive endodermal primed cells; and mixing said trophectoderm primed cells and said extra embryonic primitive endodermal primed cells with naïve PSCs under conditions that allow formation of aggregated cells. Also provided are articles of manufactures, mixtures and aggregates of cells and methods of using same.

Abstract: There is provided a display substrate and a display device. The display substrate includes a first metal layer, a first insulating layer, a metal oxide layer, a second insulating layer and a second metal layer which are stacked; wherein the metal oxide layer comprises a first pattern, a second pattern and a capacitance pattern, the first metal layer comprises a first electrode plate, there is at least a first overlapping region between the first electrode plate and the capacitance pattern to form a first storage capacitor, the second metal layer comprises a second electrode plate, there is at least a second overlapping region between the second electrode plate on the base substrate and the capacitance pattern to form a second storage capacitor, and the first electrode plate and the second electrode plate have same potential.

Abstract: A recombinant bacteria which is genetically modified to express formate dehydrogenase (FDH), phosphoribulokinase (prk) and Ribulose-Bisphosphate Carboxylase/oxygenase (RuBisCo) is disclosed. The bacteria may be modified to be autotrophic.

Abstract: Provided is a node diaphragm scraping and sorting device for a bamboo split, which is configured to scrape node diaphragms of the bamboo splits and to sequentially sort the bamboo inner layers and bamboo outer layers of the bamboo splits towards the same direction. The device includes a scraping device, a sorting device and a clamping and conveying device which are arranged from front to back along an axis. The scraping device includes a conical cylinder, two pressing semi-rings, and a scraping ring. The sorting device includes an e-shaped sleeve composed of an inner cylinder and an outer cylinder, and two shifting forks located at both ends of the sleeve. The clamping and conveying device includes an inner ring moving on the axis, two clamping semi-rings and a conveying power device. The structure, function and technical parameters of each branch device are also introduced in detail.

Abstract: The present disclosure a temperature-resistant and salt-resistant modified nano-graphite dispersed particle gel system with a strong self-growth effect.

Abstract: A pulse width modulation (PWM) circuit, a method for PWM, and an electronic device are provided. In the PWM circuit, a control word providing circuit can generate, based on an obtained target duty cycle, two target frequency control words with a ratio of the target duty cycle, and output the two target frequency control words to a pulse generation circuit, wherein a ratio of the first target frequency control word to the second target frequency control word is the target duty cycle; and the pulse generation circuit can output a target pulse signal with the target duty cycle under the control of the two target frequency control words.

Abstract: A device for a power opening tailgate of a vehicle includes an attachment means mountable to a vehicle wall at a first side of the vehicle wall for supporting a working cylinder for opening the tailgate, and a component for reinforcement of the vehicle wall. The reinforcement component is mountable to the vehicle wall at a second side of the vehicle wall, which second side is opposite to the first side of the vehicle wall, and the attachment means and the reinforcement component are mechanically connectable to each other via a through hole of the vehicle wall.

Abstract: A safety gate is configured to be mounted at a gateway and has a frame and a gate body. The frame is configured to be mounted between two walls disposed at two sides of the gateway. The frame has two sides and two first positioning assemblies respectively disposed at the two sides of the frame. The gate body is disposed in the frame and has two sides and two first pivot assemblies respectively disposed at the two sides of the gate body. The first pivot assembly at each side of the gate body is configured to detachably and pivotally connect with the first positioning assembly at a respective one of the sides of the frame.

Abstract: Disclosed is a detachable inflatable sofa with a plurality of air cavities, including a sofa cover and a plurality of inflatable air cavities, wherein each adjacent two of the air cavities are detachably connected, and all the air cavities are connected to form a body of the sofa; and the sofa cover is sleeved on an outer surface of the body. The air cavities are detachably connected and are then fixed and shaped through the sofa cover, so that the detachable inflatable sofa is convenient to disassemble and assemble, transport and early. Moreover, if a certain air cavity is damaged, it can be replaced independently, so that the usage cost is saved.