Abstract: The present invention provides pea protein and compositions comprising pea protein for use in the prevention and/or treatment of autoimmune arthritis. The invention also provides said compositions for use in combination therapy with an antirheumatic drug. The invention also provides compositions comprising pea protein, alpha-glucooligosaccharide, acacia gum, and an antirheumatic drug, and their use as a medicament. The compositions of the invention are particularly useful for treating rheumatoid arthritis.
Type:
Application
Filed:
May 15, 2023
Publication date:
March 21, 2024
Applicant:
DEVINTEC SAGL
Inventors:
Miguel Angel Alonso Cohen, Rossana Sidoti, Bhavna Karnani
Abstract: The object of the invention is topical compositions comprising pea proteins and polyphenols and the use thereof for the treatment of local or generalised disorders caused by increased permeation of the natural epithelial barriers. Said disorders may be of bacterial, viral, inflammatory, allergic and/or fungal origin, or endogenous or idiopathic.
Type:
Application
Filed:
September 11, 2023
Publication date:
December 28, 2023
Applicant:
DEVINTEC SAGL
Inventors:
Miguel Angel Alonso Cohen, Marco Di Fulvio
Abstract: The object of the invention is topical compositions comprising pea proteins and polyphenols and the use thereof for the treatment of local or generalised disorders caused by increased permeation of the natural epithelial barriers. Said disorders may be of bacterial, viral, inflammatory, allergic and/or fungal origin, or endogenous or idiopathic.
Type:
Grant
Filed:
December 21, 2020
Date of Patent:
November 7, 2023
Assignee:
DEVINTEC SAGL
Inventors:
Miguel Angel Alonso Cohen, Marco Di Fulvio
Abstract: The object of the invention is topical compositions comprising pea proteins and polyphenols and the use thereof for the treatment of local or generalised disorders caused by increased permeation of the natural epithelial barriers. Said disorders may be of bacterial, viral, inflammatory, allergic and/or fungal origin, or endogenous or idiopathic.
Type:
Application
Filed:
December 21, 2020
Publication date:
February 9, 2023
Applicant:
DEVINTEC SAGL
Inventors:
Miguel Angel Alonso Cohen, Marco Di Fulvio
Abstract: The invention provides a process for preparing a protein-polysaccharide conjugated product comprising: (a) preparing a mixture comprising pea protein, polysaccharide, and an appropriate polar solvent; wherein: the weight ratio between polysaccharide and protein is comprised from 20:80 to 60:40, and the pH of the solution is comprised from 8.0 to 10.5; and performing a Maillard reaction by heating the solution resulting from step (a) at an appropriate temperature for the necessary period of time to conjugate the protein and the polysaccharide. The invention further provides a conjugated product obtainable by the process of the invention, as well as pharmaceutical compositions comprising the conjugate and to their use in the treatment in gastrointestinal disorders. The conjugate of the invention shows a remarkable improvement in preventing and/or treating intestinal diseases, such as mucositis.
Type:
Grant
Filed:
May 8, 2017
Date of Patent:
September 22, 2020
Assignee:
DEVINTEC SAGL
Inventors:
Miguel Angel Alonso Cohen, Marco Di Fulvio