Patents Assigned to DexCom, Inc.
  • Patent number: 11943876
    Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: March 26, 2024
    Assignee: DexCom, Inc.
    Inventors: Jason Halac, John Charles Barry, Becky L. Clark, Chris W. Dring, John Michael Gray, Kris Elliot Higley, Jeff Jackson, David A. Keller, Ted Tang Lee, Jason Mitchell, Kenneth Pirondini, David Rego, Ryan Everett Schoonmaker, Peter C. Simpson, Craig Thomas Gadd, Kyle Thomas Stewart, John Stanley Hayes
  • Patent number: 11937927
    Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: March 26, 2024
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, Robert J. Boock, Sebastian Bohm, James H. Brauker, Paul V. Neale
  • Publication number: 20240090802
    Abstract: A continuous (multi-)analyte sensor device is provided, comprising a (multi-)analyte sensor operably coupled to a signal transducer, the (multi-)analyte sensor comprising at least one membrane, the least one membrane comprising a least one first transducing element, and at least one of a mediator and/or a regenerative cofactor.
    Type: Application
    Filed: September 1, 2023
    Publication date: March 21, 2024
    Applicant: DexCom, Inc.
    Inventors: Devon M. Headen, Joshua Ray Windmiller, Avid Najdahmadi, Sylvie Liong, Peter C. Simpson, Shannon Reuben Woodruff, Christina Rodriguez, Jiong Zou
  • Patent number: 11931188
    Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: March 19, 2024
    Assignee: Dexcom, Inc.
    Inventors: Esteban Cabrera, Jr., Lauren Danielle Armenta, Scott M. Belliveau, Jennifer Blackwell, Leif N. Bowman, Rian Draeger, Arturo Garcia, Timothy Joseph Goldsmith, John Michael Gray, Andrea Jean Jackson, Apurv Ullas Kamath, Katherine Yerre Koehler, Paul Kramer, Aditya Sagar Mandapaka, Michael Robert Mensinger, Sumitaka Mikami, Gary A Morris, Hemant Mahendra Nirmal, Paul Noble-Campbell, Philip Thomas Pupa, Eli Reihman, Peter C. Simpson, Brian Christopher Smith, Atiim Joseph Wiley
  • Patent number: 11925484
    Abstract: A device for generating alerts for Hypo and Hyperglycemia Prevention from Continuous Glucose Monitoring (CGM) determines a dynamic risk based on both information of glucose level and a trend obtainable from a CGM signals. The device includes a display whose color depends on the DR (for example, red for high DR, green for low risk). When DR exceeds a certain threshold, alerts are generated to suggest the patient to pay attention to the current glucose reading and to its trend, both of which are shown on the display in numbers and symbols (e.g. an arrow with different slope or color).
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: March 12, 2024
    Assignee: Dexcom, Inc.
    Inventors: Giovanni Sparacino, Claudio Cobelli, Stefania Guerra, Andrea Facchinetti, Michele Schiavon
  • Publication number: 20240074682
    Abstract: Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo are provided herein. In some examples, a device includes an indwelling sensor and sensor electronics. The sensor may include a substrate; a first electrode disposed on the substrate; an ionophore disposed on the substrate to selectively transport the target ion to or within the first electrode; and a second electrode disposed on the substrate. The sensor electronics is configured to generate a signal corresponding to an electromotive force which is at least partially based on a potential difference that is generated between the first electrode and the second electrode responsive to the ionophore transporting the target ion to the first electrode.
    Type: Application
    Filed: September 1, 2023
    Publication date: March 7, 2024
    Applicant: DexCom, Inc.
    Inventors: Berta Esteban Fernandez de Avila, Devon M. Headen, Stacy Hunt DuVall, Jiong Zou, Shane Richard Parnell, Nicholas Vincent Apollo, Joshua Ray Windmiller
  • Patent number: 11918354
    Abstract: Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: March 5, 2024
    Assignee: DEXCOM, INC.
    Inventors: Peter C. Simpson, Robert J. Boock, Matthew Wightlin, Mark C. Shults
  • Publication number: 20240066223
    Abstract: Automatic suspension and resumption of medicament delivery is described. In one or more implementations, a request to suspend delivery of a medicament to a user is received. A medicament delivery system is controlled to suspend delivery of the medicament to the user, and to automatically resume medicament delivery to the user after a suspension time period. In one or more implementations, a medicament delivery system is controlled to suspend delivery of a medicament to a user during performance of an activity, and to automatically resume delivery of the medicament to the user after performance of the activity is completed. In one or more implementations, a medicament delivery system is controlled to suspend medicament delivery to a user at a first time based on a location of the user, and to resume medicament delivery to the user at a second time based on a subsequent location of the user.
    Type: Application
    Filed: July 29, 2023
    Publication date: February 29, 2024
    Applicant: Dexcom, Inc.
    Inventor: Nathanael R. Paul
  • Patent number: 11903697
    Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: February 20, 2024
    Assignee: DEXCOM, INC.
    Inventors: Naresh C. Bhavaraju, Michael A. Bloom, Leif N. Bowman, Alexandra Lynn Carlton, Katherine Yerre Koehler, Hari Hampapuram, Lauren Hruby Jepson, Jonathan Hughes, Apurv Ullas Karnath, Anna Leigh Davis, Peter C. Simpson, Stephen J. Vanslyke
  • Patent number: 11896374
    Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: February 13, 2024
    Assignee: Dexcom, Inc.
    Inventors: Apurv Ullas Kamath, Peter C. Simpson, Mark Brister
  • Publication number: 20240041356
    Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the devices include a membrane that has an interference domain designed to reduce the permeation of one or more interferents.
    Type: Application
    Filed: July 7, 2023
    Publication date: February 8, 2024
    Applicant: DexCom, Inc.
    Inventors: Jonathan Hughes, Robert J. Boock, Chris W. Dring
  • Patent number: 11892426
    Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: February 6, 2024
    Assignee: Dexcom, Inc.
    Inventors: Michael J. Estes, Jennifer Blackwell, Sebastian Bohm, Robert J. Boock, Jack Pryor, Peter C. Simpson, Matthew D. Wightlin
  • Patent number: 11883126
    Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: January 30, 2024
    Assignee: Dexcom, Inc.
    Inventors: Arturo Garcia, Peter C Simpson, Apurv U Kamath, Naresh C. Bhavaraju, Stephen J. Vanslyke
  • Patent number: 11887715
    Abstract: Adaptive on board estimation of exogenous pharmacon responsive to transient (i.e., impermanent) physiological effects is provided. Dynamically estimating an equivalent amount of an exogenous pharmacon on board (XOB), such as insulin and/or carbohydrates, left in the subject, is based on predictions of glucose time-series data. These estimated values, such as insulin on board (IOB), are useful for diabetes management software, including decision support and/or artificial pancreas (AP) algorithms, for example.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: January 30, 2024
    Assignee: DEXCOM, INC.
    Inventors: Stephen D. Patek, Enrique Campos-Náñez
  • Patent number: 11883164
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: January 12, 2022
    Date of Patent: January 30, 2024
    Assignee: Dexcom, Inc.
    Inventors: Apurv U Kamath, Jack Pryor, Paul V. Goode, Jr., James H Brauker, Aarthi Mahalingam
  • Patent number: 11879887
    Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: January 23, 2024
    Assignee: Dexcom, Inc.
    Inventors: Naresh C. Bhavaraju, Arturo Garcia, Hari Hampapuram, Apurv Ullas Kamath, Aarthi Mahalingam, Dmytro Sokolovskyy, Stephen J. Vanslyke
  • Publication number: 20240021284
    Abstract: Location-aided glycemic control is described. A glycemic control system obtains sensor data is from one or more sensors, and detects a location of a user based on the sensor data. The glycemic control system predicts an activity that the user will perform at the location based on the location of the user, and generates a recommendation to control a glycemic response of the user to the predicted activity. In one or more implementations the glycemic control system causes display of the recommendation to control the glycemic response of the user. In one or more implementations the recommendation corresponds to administering an amount of a medicament to the user to control the glycemic response to the predicted activity, and the glycemic control system communicates instructions to a medicament delivery system which causes the medicament delivery system to administer the amount of the medicament to the user.
    Type: Application
    Filed: July 11, 2023
    Publication date: January 18, 2024
    Applicant: Dexcom, Inc.
    Inventors: Nathanael R. Paul, Apurv ULLAS Kamath
  • Patent number: 11872034
    Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: January 16, 2024
    Assignee: DEXCOM, INC.
    Inventors: Derek James Escobar, Naresh C. Bhavaraju, Gary A. Morris, Jorge Valdes
  • Patent number: 11872036
    Abstract: Sleeves and cases for protecting medical devices against contamination, and methods for cleaning and disinfecting medical devices are provided. The various embodiments enable a single medical device to be used by more than one patient successively while reducing the risk of disease transmission from patient to patient.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: January 16, 2024
    Assignee: DexCom, Inc.
    Inventors: Nicholas Polytaridis, David J. Carner, Jacob S. Leach, Christina Orsini
  • Patent number: 11864891
    Abstract: Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: January 9, 2024
    Assignee: DEXCOM, INC.
    Inventors: Robert J. Boock, Chris W. Dring