Abstract: The present invention relates generally to variable stiffness transcutaneous medical devices including a distal portion designed to be more flexible than a proximal portion. The variable stiffness can be provided by a variable pitch in one or more wires of the device, a variable cross-section in one or more wires of the device, and/or a variable hardening and/or softening in one or more wires of the device.
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Grant
Filed:
August 1, 2003
Date of Patent:
August 17, 2010
Assignee:
DexCom, Inc.
Inventors:
Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
Type:
Grant
Filed:
March 26, 2007
Date of Patent:
August 17, 2010
Assignee:
DexCom, Inc.
Inventors:
Mark Brister, Sean Saint, James R. Petisce, Mark Shults, Jacob S. Leach, David K. Wong, Kum Ming Woo
Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
Type:
Application
Filed:
April 19, 2010
Publication date:
August 12, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark C. Shults, Stuart J. Updike, Rathbun K. Rhodes
Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
Type:
Application
Filed:
April 19, 2010
Publication date:
August 12, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark C. Shults, Stuart J. Updike, Rathbun K. Rhodes
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. In some embodiments, a device is provided for monitoring glucose concentration in a host, including a continuous glucose sensor and an integrated receiver including a single point glucose monitor. In some embodiments, a computer system is provided that determines a rate of change of continuous analyte sensor data.
Type:
Grant
Filed:
January 18, 2006
Date of Patent:
August 10, 2010
Assignee:
DexCom, Inc.
Inventors:
James H. Brauker, Apurv Ullas Kamath, Paul V. Goode, Mark Brister
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.
Type:
Grant
Filed:
May 1, 2008
Date of Patent:
August 10, 2010
Assignee:
DexCom, Inc.
Inventors:
Mark C. Shults, Rathburn K. Rhodes, Stuart J. Updike, James H. Brauker
Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
Type:
Application
Filed:
April 14, 2010
Publication date:
August 5, 2010
Applicant:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, JR., Mark Brister, Paul V. Neale, Sean Saint
Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
Type:
Application
Filed:
April 14, 2010
Publication date:
August 5, 2010
Applicant:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, JR., Mark Brister, Paul V. Neale, Sean Saint
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
Type:
Application
Filed:
March 19, 2010
Publication date:
July 29, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark Brister, Paul V. Neale, James Brauker
Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
Type:
Application
Filed:
March 26, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark Brister, James R. Petisce, Peter Simpson
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Application
Filed:
March 23, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Application
Filed:
March 23, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Application
Filed:
March 23, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
Type:
Application
Filed:
March 30, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark Brister, Paul V. Neale, Sean Saint, James R. Petisce, James Patrick Thrower, Apurv Ullas Kamath, Daniel S. Kline, John A. Guerre, Daniel Shawn Codd, Thomas F. McGee, David Michael Petersen
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
Type:
Application
Filed:
March 29, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Mark Brister, Steve Masterson, J. Michael Dobbles, Michael Robert Mensinger, Sean Saint, Apurv Ullas Kamath
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Application
Filed:
March 26, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
Type:
Application
Filed:
March 29, 2010
Publication date:
July 22, 2010
Applicant:
DexCom, Inc.
Inventors:
Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathburn K. Rhodes, Mark A. Tapsak
Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
Type:
Grant
Filed:
March 27, 2007
Date of Patent:
July 20, 2010
Assignee:
DexCom, Inc.
Inventors:
Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathbun K. Rhodes, Mark A. Tapsak
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
Type:
Application
Filed:
March 23, 2010
Publication date:
July 15, 2010
Applicant:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, James Brauker, J. Michael Dobbles