Abstract: An applicator syringe for containing and dispensing moisture-sensitive or moisture-reactive adhesives comprises a generally sealed barrel containing a plunger having a non-stick polymeric seal and a hydrocarbon grease disposed between the seal and the adhesive contained in the barrel. As the plunger advances in the barrel, a sealing, thin film of the hydrocarbon grease is deposited on the interior walls of the syringe barrel to provide a moisture-impervious seal between the polymeric seal and barrel and to aid in smooth advancement of the plunger in the barrel.